Hairy cell leukemia is a cancer of the white blood cells that responds to treatment with drugs that inhibit dna synthesis. A mutation in the braf gene, designated braf v600e, is associated with hairy cell leukemia. Braf v600e differs from the nonmutant braf gene in a single base pair. Imagine that this change to the single base-pair added a hae iii restriction site indicated by the arrow on the gene below. You decide to identify hairy cell leukemia with pcr and the restriction enzyme hae iii.

Answers

Answer 1

In Hairy cell leukemia, a cancer of the white blood cells, a mutation in the BRAF gene called BRAF V600E, which is connected to the disease, can be found. This differs from the normal BRAF gene in a single base pair.

A restriction site called Hae III was added to the single base-pair as a result of the change, as indicated by the arrow on the gene shown below. In the identification of hairy cell leukemia, PCR and the restriction enzyme Hae III were used. Hairy cell leukemia is a type of cancer of the white blood cells that is easily treated using DNA synthesis-inhibiting drugs. The BRAF V600E mutation in the BRAF gene is related to hairy cell leukemia. This variation is only one base pair different from the nonmutant BRAF gene.

When a Hae III restriction site is added to the single base-pair modification, as shown by the arrow in the gene image, a particular method for identifying hairy cell leukemia with PCR and the restriction enzyme Hae III is produced. Polymerase Chain Reaction (PCR) is a well-known molecular biology technique that can be used to replicate tiny sections of DNA quickly. Restriction enzymes cleave DNA at specific sites, and they are commonly used in conjunction with PCR to help identify DNA sequences.

A base pair change in the BRAF gene, which is associated with hairy cell leukemia, was described in the question. Hae III restriction site was introduced to the single base-pair alteration caused by this mutation, as indicated by the arrow in the gene illustration. To identify hairy cell leukemia using PCR and the Hae III restriction enzyme, this change is significant.

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Related Questions

fill in the blank. a person who has limitations of learning and difficulty with social skills and behavior control is most likely to be suffering from a disorder.

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A person who struggles with social skills, behavior management, and learning disabilities is most likely experiencing a neurodevelopmental problem.

What neurodevelopmental condition is the most prevalent?

An approximated 5 to 7 20% of all children of school age are thought to be affected by ADHD, the most prevalent neurodevelopmental condition in childhood. ADHD often appears before the age of 7, however symptoms may not become apparent until a kid is a little older and faces more difficult social and academic conditions.

A mental disease or neurodevelopmental disorder?

The term "neurodevelopmental disorders" (NDs) refers to a group of conditions that affect neurological development and the way the brain works, impairing social, cognitive, and function. The most prevalent NDs are attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disease (ASD) (ADHD).

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What is a red blood cell

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Answer:

Red blood cells carry oxygen from our lungs to the rest of our bodies. Then they make the return trip, taking carbon dioxide back to our lungs to be exhaled. Schedule an appointment.

a nurse is making a home visit to a postpartum client. which finding would lead the nurse to suspect that a woman is experiencing postpartum psychosis?

Answers

The finding that would lead the nurse to suspect that a woman is experiencing postpartum psychosis is the sudden development of delusions and hallucinations.

The term "postpartum psychosis" refers to a rare but severe mental illness that can affect a woman after giving birth. It is frequently marked by delusions, hallucinations, and other symptoms of psychosis.

The following are some signs that a woman is experiencing postpartum psychosis:

Sudden development of delusions and hallucinations Believing that her baby is dead or missing, that someone is plotting against her or her baby, or that she has committed a crime Loss of touch with reality or being unsure of what is real or not Rapid mood swings, agitation, and disorientation  Difficulty sleeping and nightmares are all common symptoms

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little confused SOMEONE TELL ME <3
someone please hurry my time is running out !!!

little confused SOMEONE TELL ME &lt;3someone please hurry my time is running out !!!

Answers

B. Leaving without telling the boss is irresponsible and could cause her some issues. She cannot wear a hat that is too big because in a dangerous environment something that is not fit for you causes more danger. Leaving during lunch is bad because she’s supposed to wear it at all times. Not working on dangerous machinery also doesn’t work for if she’s required to wear it at all time it’s not just the machines that cause danger.

effects of paracetamol on enzymes involved in the pain

Answers

Answer:

vomiting,possibly blood in vomit,muscle spasms,

Explanation:

In which situation would the nurse consider family members as the primary source of information?

Answers

The nurse regards family members as that of the main source of information.

2 The client is an infant or child.

3 The client is brought in as an emergency.

4 The client is critically ill and disoriented.

The correct option are 2,3,4.

What is infant?

An infant is a formal or specialized synonym for the colloquial term baby, which refers to human beings' extremely young progeny. This word can also refer to the juvenile offenders of other organisms.. A newborn is an infant who is only a few hours, days, or up to a month old.

What is critically ill?

Critical illness is a potentially fatal multisystem condition that can cause considerable morbidity or mortality. Most patients have a period of physiological deterioration before developing critical illness; however, data suggests that the early indicators of this are usually missed.

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I understand that the question you are looking for is:

When should the nurse consider family members as the primary source of information? Select all that apply

1 The client is an elderly adult.

2 The client is an infant or child.

3 The client is brought in as an emergency.

4 The client is critically ill and disoriented.

5 The client visits the outpatient department

whats the consistency of sperm

Answers

Healthy semen is usually a cloudy-white or grey fluid with a jelly-like consistency

Which sequence correctly traces the path of urine after it leaves the kidneys?
a. ureters, urinary bladder, urethra
b. urinary bladder, ureters, urethra
c. urethra, urinary bladder, ureters
d. urinary bladder, urethra, ureters

Answers

The sequence which correctly traces the path of urine after it leaves the kidneys is option a. ureters, urinary bladder, urethra.

Urine travels through the ureter, a channel, from the kidney to the bladder. Each kidney typically has one ureter. A small tube, the ureter is around 12 inches (30 cm) long on either side. The diameter of a ureter varies significantly at different locations throughout its length, and it has thick contractile walls.

The urethra is a tube that carries urine from the body by joining the urinary meatus and bladder. The urethra passes through the pen.is and carries semen in males. The urethra joins the urinary meatus above the vagina in females. Males utilise their urethra for both urine and eja.culation, but females just use it for urination.

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why do medications require different routes into the body

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Other routes of administration are required when the oral route cannot be used, for example: When a person cannot take anything by mouth. When a drug must be administered rapidly or in a precise or very high dose. When a drug is poorly or erratically absorbed from the digestive tract.

Which parasite is transmitted through the predator-prey route?

OA

Toxocara canis

OB.

Ancylostoma caninum

O C.

lice

OD.

Echnicoccus

O E.

Trichomonas

Answers

Answer:

Toxocara canis

Explanation:

Predator prey route is the transmission method used by different protozoa. They enter the body of the prey when they eat an infected prey. They are infused in the blood of the predator and then resides there forming an infection. They overcome transmission barriers and enters the body of host.

incretin‑based therapy and risk of cholangiocarcinoma: a nested case–control study in a population of subjects with type 2 diabetes

Answers

A rеcеnt study found that usе of incrеtin-basеd thеrapy may bе associatеd with an incrеasеd risk of cholangiocarcinoma, although thе absolutе risk is small. Thе risk appеarеd to bе highеst in subjеcts who had bееn using incrеtin-basеd thеrapy for longеr pеriods of timе and in thosе who had a history of gallstonеs

Incrеtin-basеd thеrapy is a typе of mеdication usеd to trеat typе 2 diabеtеs. It works by stimulating thе rеlеasе of insulin and rеducing glucagon lеvеls, which hеlps to lowеr blood sugar lеvеls.

Thе study usеd a nеstеd casе-control dеsign, which mеans that casеs of cholangiocarcinoma wеrе idеntifiеd and thеn matchеd with control subjеcts basеd on cеrtain charactеristics.

Thе study found that usе of incrеtin-basеd thеrapy was associatеd with an incrеasеd risk of cholangiocarcinoma, although thе absolutе risk was small. Thе risk appеarеd to bе highеst in subjеcts who had bееn using incrеtin-basеd thеrapy for longеr pеriods of timе and in thosе who had a history of gallstonеs.

In summary, Incrеtin-basеd thеrapy is a typе of mеdication usеd to trеat typе 2 diabеtеs. It works by stimulating thе rеlеasе of insulin and rеducing glucagon lеvеls, which hеlps to lowеr blood sugar lеvеls.

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The body's first line of defense is formed by the:

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Answer: 1. The Epidermis. The epidermis is the water-resistant outer layer of skin and the body's first line of defense against environmental elements, ultraviolet, tradiation, bacteria, and other germs.30 ene. 2020

If a manual defibrillator is not available for an infant victim, which action should you take? a) perform CPR for two minutes before calling for help b) perform CPR for one minute before calling for help c) call for help immediately d) give the infant

Answers

If a manual defibrillator is not available for an infant victim, the best action to take is to call for help immediately.

Time is of the essence when dealing with a cardiac emergency, and waiting to perform CPR can be detrimental to the infant's survival.While performing CPR can help maintain blood flow and oxygen to the infant's vital organs, it is not a replacement for defibrillation in cases of cardiac arrest. Defibrillation is the process of delivering an electrical shock to the heart to restore its normal rhythm. Without defibrillation, the chances of survival for an infant victim of cardiac arrest decrease significantly.Therefore, it is crucial to call for help immediately and follow any instructions given by the emergency dispatcher. They can guide you through the steps of performing CPR until medical professionals arrive with a defibrillator or other necessary equipment.

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If a manual defibrillator is not available for an infant victim, the best course of action would be to call for help immediately.

While performing CPR is important, it may not be as effective as a defibrillator when dealing with certain heart conditions. Therefore, it is crucial to get medical professionals on the scene as soon as possible to provide further assistance. Additionally, it is important to note that using a defibrillator on an infant requires specialized training and equipment, so attempting to use one without proper knowledge and resources could potentially harm the infant. In the meantime, performing CPR can help to keep the blood and oxygen flowing until help arrives. Remember to always prioritize calling for help as soon as possible in any emergency situation.

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List all the bones on your thumb from proximal to distal. Do the same for your pinky finger.
What is the difference?

Answers

Answer:

Thumb= distal phalanx, promixal phalanx,  metacarpal

Pinky= distal phalanges ,middle phalanges,  prominal phalanges, metacarpal

Explanation:

Thumb bone from proximal to distal. Daumen = distale Phalanx, proximale Phalanx, Mittelhandknochen

Pinky = distale Phalangen, mittlere Phalangen, pronominale Phalangen, Mittelhandknochen.

What are the 14 phalanges?

The phalange is one of the bones of the fingers and toes. Beim Menschen gibt es 14 Fingerglieder in jeder Hand und jedem Fuß, 2 in jedem Daumen und großen Zeh und 3 in den verbleibenden Fingern. They are connected to the metacarpal bones of the hands and the metatarsals of the feet.

What is a phalange?

The phalanges are the bones that make up the fingers and toes. The human body has 56 phalanges, and each hand and foot has 14 phalanges. Each finger and toe has three phalanges, except that there are only two big toes and two big toes.

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which instructions will the home health nurse include when teachinga client with peripheral atery disease

Answers

Crossing the legs and using compression stockings will restrict blood flow, so these actions should be avoided in clients with peripheral artery disease. , Inspection of the feet is done daily to detect injury, infection, or skin breakdown. The correct option (a,b,d)

An accumulation of fatty deposits in the arteries known as peripheral artery disease (PAD) makes it difficult for blood to reach the leg muscles. Other names for it include peripheral vascular disease (PVD).

What causes peripheral artery disease primarily?

Atherosclerosis, the accumulation of fatty plaque in the arteries, is the primary cause of it. While PAD can occur in any blood artery, it tends to affect the legs more frequently than the arms.

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Full Question: Which instructions will the home health nurse include when teaching a client with peripheral artery disease? Select all that apply.

A. "Avoid crossing your legs."

B. "Inspect your feet daily."

C. "Change positions slowly."

D. "Do not use compression stockings."

E. "Avoid green leafy vegetables in your diet."

witch of the fallowing is an advantige of synthetic fiber rope

Answers

Answer:

It's safer, lighter, faster and easier.

Explanation:

You diagnose AOM with severe symptoms in a 22-month-old male patient who weighs 20 kg (44 lb). What is the most appropriate treatment?

Answers

The most appropriate treatment for a 22-month-old male patient diagnosed with acute otitis media (AOM) and severe symptoms would be a course of antibiotics.

The dosage and duration of treatment would depend on the specific antibiotic chosen by the healthcare provider, taking into consideration the patient's weight of 20 kg (44 lb). Pain relief medication such as acetaminophen or ibuprofen may also be recommended to manage any discomfort associated with AOM. It is important to closely monitor the patient's symptoms and follow up with a healthcare provider if there is no improvement or if symptoms worsen. The first-line choice for this patient is Amoxicillin, at a dose of 45-90 mg/kg/day, divided into two daily doses. Since the patient weighs 20 kg, the recommended dosage would be 900-1800 mg per day, divided into two doses. It is essential to consult a healthcare professional for the appropriate prescription and guidance.

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psychology is considered as what type of science?

psychology is considered as what type of science?

Answers

Answer: social studies, social science.

Explanation:

The answers is Medicine

A 0.34mi dose of a drug is injected into a patient steadily for 0.65 seconds. At the end of this time, the quantity, Q.of the drug in the body starts to decay exponentially at a continuous rate of 0.5% as a function of time, t1​ in seconds. Then, Q(t)={ if 0≤t≤0.65​ if ≤t<[infinity]​ Inpout an expression below (oo nor nouac) Consider a car whose position, s, is given by the table Then. the average velocity over the interval 0≤t≤10 is the velocity at t=10 is Note: Your answers should be numbers and units. Find the smallest value of the constant k such that the indicated limit exists limx→[infinity]​ekx+7315x−85​ (If any value of k will work, enter any; if none will work, enter none.) Answer: smallest k= Are there any other values of k that will work?

Answers

The smallest value of the constant k such that the indicated limit exists is k = 85.

To find the smallest value of k that makes the limit exist, we need to analyze the expression: lim(x→∞) ekx + 7315x - 85.

First, let's consider the exponential term, ekx. As x approaches infinity, the exponential term will grow exponentially. To ensure the exponential term does not dominate the expression, we need k to be small. Therefore, the smallest value of k that works is k = 0.

Next, let's consider the linear term, 7315x. As x approaches infinity, the linear term will grow linearly. Since the exponential term dominates as k approaches 0, the linear term becomes negligible.

Finally, we have the constant term, -85. As x approaches infinity, the constant term remains unchanged.

Combining all these factors, we can conclude that the smallest value of k that makes the limit exist is k = 85.

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How long should a general warm-up involving moderate intensity last before beginning vigorous activity

Answers

Answer:

See Explanation

Explanation:

The time you commit to your warm-up should be relative to your level of involvement in your particular sport. So, for people just looking to increase their general level of health and fitness, a minimum of five to ten minutes would be enough.

How can you tell whether a fat contains primarily saturated or unsaturated fatty acids?
a. All plant oils are unsaturated because they are liquid at room temperature.
b. Solid fats that melt at a high temperature are unsaturated.
c. Oils that remain liquid at room temperature are primarily unsaturated.
d. Beef fat is considered unsaturated because cattle eat only plant foods.
e. all fat that is solid at low temperatures is unsaturated.

Answers

Heat the fat until it liquefies, then use a gas chromatograph to separate the fatty acids. This is the simplest method for accomplishing this (GC).

What distinguishes a fat as being saturated or unsaturated? Heat the fat until it liquefies, then use a gas chromatograph to separate the fatty acids. This is the simplest method for accomplishing this (GC).At the carbon-carbon double bond, saturated fatty acids will have a distinctive double-bonded carbon atom, whereas unsaturated fatty acids won't.A saturated fat.It is solid when left at room temperature.It can be present in full-fat dairy products, such as yogurt and cheese, as well as high-fat meats like butter and lard.Unsaturated fatAt normal room temperature, this is usually liquid.You can find it in fish, nuts, and vegetable oils.The largest number of hydrogen atoms are found in saturated fats, but there are less hydrogen bonds than the maximum amount at each double bond in unsaturated fats.

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The best way to tell whether a fat contains primarily saturated or unsaturated fatty acids is to look at the physical properties of the fat. Solid fats that melt at a high temperature are unsaturated, while oils that remain liquid at room temperature are primarily unsaturated.

What is fatty acids?

Fatty acids are organic compounds that are made up of a carboxylic acid group attached to a hydrocarbon chain. They are found naturally occurring in plant and animal fats, oils, and waxes, and are important components of biological membranes. Fatty acids are essential for the production of energy and for the proper functioning of all cells and organs. In humans, fatty acids are used to make hormones and regulate many bodily processes. They are also important for the absorption of fat-soluble vitamins and the synthesis of lipids.

Fats that are solid at low temperatures are saturated. For example, beef fat is considered saturated because it is solid at low temperatures.

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5. what is the most effective way to prevent infection when providing catheter care for a patient?

Answers

Cleanse from the meatus outward will be the most effective way to prevent infection for catheters.

It is important to wash your hands before and after handling a catheter or drainage system, and to wear clean gloves while doing so. Use only soap and water or another equally delicate cleaning solution while providing peri-care. Do avoid kinking or obstructing the catheter and tubing.

While utilizing the leg bags or the urine collection system, keep the catheter system closed. Replace disconnected catheters and urine collecting bags right away. Cathodes and urine collecting bags shouldn't be changed at regular, predetermined times. Do not regularly provide antibiotic prophylaxis.

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The nurse has provided client education about the function of the renal system. Which statements made by the client indicate an understanding of the teaching? Note: Credit will be given only if all correct choices and no incorrect choices are sel

Answers

The provided question is incomplete as it lacks the group of choices required to answer the question however, the group of choices are as follows:

A.  ​"Kidneys help the heart by balancing​ potassium."

B.  ​"Kidneys balance the fluid and electrolytes in my​ body."

C.  ​"Kidneys keep blood pressure from getting too​ low."

D.  "Kidneys help decrease infections by excreting​ bacteria."

E.  ​"Kidneys help regulate the oxygen levels in my​ blood."

Answer:

The correct answer is - A, B, and C.

Explanation:

The nurse is educating the client about the renal system and the client made these statements that express that the client understood the teaching about the renal system.

The renal system is the system that is related to the kidney and excretion. Kidneys or renal system is helpful in regulating the salts and ions such as potassium and maintain the balance of water and electrolytes in the body. The renal system also helps in regulating blood pressure and prevent it from decreasing.

Explain: why asthma attacks are considered medical emergencies
and what steps should be taken on arrival of a patient in the
midst of an asthma attack.

Answers

Asthma attacks are considered medical emergencies because due to shortness of breath, your unable to speak regularly.

1. Take medication and move away from triggers. ...
2. Ask someone to stay with you. ...
3. Sit upright and try to stay calm. ...
4. Continue using rescue medication as instructed.

What are the requirements when checking in C3-5 products

Answers

Handwritten marks such as circles, checkmarks, slashes, and so on are required.

What are C3-5 and pse?

The C3-5 and Pse are certificates that give the products a grade. Using CFRX, all Cill-Vs should be checked into the electronic delivery check-in screen.

Each page of the invoice contains a signature. Each page of the invoice must include the date received.

The date when the Ciii-v and Pse products were obtained must be documented on each page of the invoice.

As a result, the prerequisites are handwritten marks such as circles, checkmarks, slashes, and so on.

Thus, these are the basic requirements when checking in C3-5 products.

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List 11 body systems and give:

The main function of the system
• One disorder associated with the system listed
• One test ordered for the disorder listed
• The color top tube the sample is collected in for the disorder listed
• The laboratory department the sample is analyzed in

Answers

Answer:

Diagnostic tests and procedures are vital tools that help physicians confirm or rule out a neurological disorder or other medical condition. A century ago, the only way to make a definite diagnosis for many neurological disorders was to perform an autopsy after someone had died. Today, new instruments and techniques allow scientists to assess the living brain and monitor nervous system activity as it occurs. Doctors now have powerful and accurate tools to better diagnose disease and to test how well a particular therapy may be working.

Perhaps the most significant changes during the past 10 years have occurred in genetic testing and diagnostic imaging. Much has been learned from sequencing the human genome (the complete set of a person’s genes) and developing new technologies that detect genetic mutations. Improved imaging techniques provide high-resolution images that allow physicians to view the structure of the brain. Specialized imaging methods can visualize changes in brain activity or the amounts of particular brain chemicals. Scientists continue to improve these methods to provide more detailed diagnostic information.

Researchers and physicians use a variety of diagnostic imaging techniques and chemical and metabolic tests to detect, manage, and treat neurological disease. Many tests can be performed in a physician’s office or at an outpatient testing facility, with little if any risk to the person. Some procedures are performed in specialized settings to determine particular disorders or abnormalities. Depending on the type of test, results may be immediate or may take time to process.

Explanation:

Where did AIDS/HIV originate? How did it move to humans?

Answers

HIV infection in humans was caused by a type of chimpanzees in Central Africa.

What is HIV/AIDS?HIV (Human Immunodeficiency Virus) is an immune-deficiency virus. (A person's immune system fights infections and diseases in the body.) HIV weakens a person's immune system over time, making it difficult to fight diseases. AIDS is caused by HIV (Acquired Immune Deficiency Syndrome).HIV, the virus that causes AIDS, had jumped from chimps to humans in Africa sometime in the early twentieth century. The earliest known case of HIV-1 infection in human blood is from a sample taken in 1959 from a man who died in Kinshasa, then in Belgian Congo.It can be passed from mother to child during pregnancy, childbirth, or breastfeeding, or through sexual contact, illicit injection drug use or needle sharing, contact with infected blood, or from mother to child during pregnancy, childbirth, or breastfeeding.

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How many amnio acids are found in nature

Answers

Answer: its 500

The key elements of an amino acid are carbon (C), hydrogen (H), oxygen (O), and nitrogen (N), although other elements are found in the side chains of certain amino acids. About 500 naturally occurring amino acids are known as of 1983 (though only 20 appear in the genetic code) and can be classified in many ways


C2
Describe the relevant values, principles or standards that relate to communication

Answers

Answer:

Communication is the exchange or transmission of information that can take place in different ways (verbal, non-verbal and paraverbal) and in different ways (speaking, writing), now also by way of computer-mediated communication.  Information in this context is a comprehensive term for knowledge, insight, experience or empathy.

In addition to its original meaning as a social act, the word communication is also used for other processes in different contexts. The increasing use of communication technology, for example, meant that technical aspects were also included in the term communication. Communication is therefore also understood to mean “data transmission”, “mutual control” and, in simple cases, “connection” of devices; in other situations, communication is related to institutions or companies and their target groups. Then no longer living beings, but instead organized units (or "systems") are viewed as communicators.

If one half of the DNA ladder is above sequence, what is the other side of the ladder’s DNA sequence?

Answers

Each strand of DNA consists of number of nucleotides. Each nucleotide is made up of Deoxyribose sugar, Phosphate group and a Nitrogen base.
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Use the key term Immunity in a sentence that explains its relationship to the era of exploration Devonte and his friends each eat 13 of 14 of a leftover apple pie. Whatfraction of the original pie does each friend get? What kind ofchange does the eaten apple pie und if we measure the speed of rotation of a system (held together by gravity) at different distances d from the center, and we find that it does not fall as but that it stays more or less flat as far as we can measure it, it means that What is the current yield for a $1,000 corporate bond that pays 13 percent and has a current market value of $880 The seats on the right side of the school bus fit two students each. The seats on the left side of the school bus can fit three students each. There are 14 rows of seats. Eight students can fit in the very back seat. How many people can ride the bus at one time (Remember to count every person)? _ owl is _ wise bird (a/an/the) A cash register contains p pennies and q quarters. Write an algebraic expression that represents the total amount of money(in dollars) Which of the following describes conditions in Germany following World War I?Germany depended on American loans to make reparations payments.Germans believed the provisions of the Versailles Treaty were too harsh.The Communists seized power from the republican government.The Nazi Party increased in popularity and promised to restore Germany's greatness. On your own sheet of grid paper (see above for link to grid paper), draw an irregular figure which has an area ofpproximately 12 square units.pls help i rlly need it100 points Fort Sumter is considered what type of fort?A. Neutral B. EnglishC. Confederate D. Union Which other letter has the same sound as the letter "b"? (Intro to Direct Variation Question) A popular hair salon disbursed daily wages of $614.88 equally among 8 shampooers. Determine the number of shampooers that were employed at the salon the following day, if the salon paid a total of 1152.90 as daily wages. What type of life policy covers two people and pays upon the death of the last insured? -Shared -Survivorship -Adjustable -Joint. -Survivorship. (5+9)+3+6(4+5)+6+9(4-3) How much heat is required to cause 15g of liquid water at its boiling point to become a gas? excerpt from Solitude by Henry David Thoreau This is a delicious evening when the whole body is one sense and imbibes delight through every pore. I go and come with a strange liberty in Nature, a part of herself. As I walk along the stony shore of the pond in my shirt sleeves, though it is cool as well as cloudy and windy, and I see nothing special to attract me, all the elements are unusually congenial to me. The bullfrogs trump to usher in the night, and the note of the whippoorwill is borne on the rippling wind from over the water. Sympathy with the fluttering alder and poplar leaves almost takes away my breath; yet, like the lake, my serenity is rippled but not ruffled. These small waves raised by the evening wind are as remote from storm as the smooth reflecting surface. Though it is now dark, the wind still blows and roars in the wood, the waves still dash, and some creatures lull the rest with their notes. The repose is never complete. The wildest animals do not repose, but seek their prey now; the fox, and skunk, and rabbit, now roam the fields and woods without fear. They are Natures watchmen, links which connect the days of animated life. . . . Some of my pleasantest hours were during the long rainstorms in the spring or fall, which confined me to the house for the afternoon as well as the forenoon, soothed by their ceaseless roar and pelting; when an early twilight ushered in a long evening in which many thoughts had time to take root and unfold themselves. . . . Men frequently say to me, I should think you would feel lonesome down there, and want to be nearer to folks, rainy and snowy days and nights especially. I am tempted to reply to such,This whole earth which we inhabit is but a point in space. How far apart, think you, dwell the two most distant inhabitants of yonder star, the breadth of whose disk cannot be appreciated by our instruments? Why should I feel lonely? Is it not our planet in the Milky Way? This which you put seems to me not to be the most important question. What sort of space is that which separates a man from his fellows and makes him solitary? I have found that no exertion of the legs can bring two minds much nearer to one another. Read this excerpt from Solitude by Henry David Thoreau. I go and come with a strange liberty in Nature, a part of herself. As I walk along the stony shore of the pond in my shirt sleeves, though it is cool as well as cloudy and windy, and I see nothing special to attract me, all the elements are unusually congenial to me. How does Thoreau distinguish the natural world, perhaps in contrast to the human world? A Nature provides him with shelter. B Nature is always alert and moving. C Nature is a place where he feels like he belongs. D Nature is predictable and ordered. Which fraction is in simplest form? 3/12 5/10 2/3 4/6 what is ruth from raisin in the sun dream? a) Why did some of the komodo dragon's eggs not hatch? ladders used to provide access to deck-forming levels must extend above the formwork at least _____.