Explain what a feedback loop is using the terms input, output, and homeostasis?

Answers

Answer 1

Feedback loops are biological mechanisms whereby homeostasis is maintained. This occurs when the product or output of an event or reaction changes the organism's response to that reaction. Positive feedback occurs to increase the change or output: the result of a reaction is amplified to make it occur more quickly.

Answer 2

Feedback loop are biological mechanism whereby homeostasis is maintained.

What is homeostasis?

Homeostasis is defined as the character of the body to maintain its internal temperature when the body experience too much cold it starts shivering to generate heat and when body feel too much heat it starts sweating to maintain heat.

The term was coined in 1930 by the physician Walter Cannon. His book, The Wisdom of the Body, describes how the human body maintains proper  levels of temperature and other vital conditions such as the water, salt, sugar, protein, fat, calcium and oxygen contents of the blood.

Homeostasis is brought about by a natural resistance to change when already in the optimal conditions, and equilibrium is maintained by many regulatory mechanisms.

All homeostatic control mechanisms have at least three interdependent components for the variable being regulated: a receptor, a control center, and an effector.

Therefore, Feedback loop are biological mechanism whereby homeostasis is maintained.

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Related Questions

Explain why most nerve cells have a myelin sheath (2 marks)​

Answers

Answer:

This allows electrical impulses to travel efficiently and quickly along the cells.

The average distance between Earth and the sun is called what?

Answers

Answer:

92,955,807 miles

Earth orbits the sun 100,000 times closer than the Oort Cloud, at an average of 92,955,807 miles (149,597,870 km). The distance from Earth to the sun is called an astronomical unit, or AU, which is used to measure distances throughout the solar system.

Answer:

the distance from the earth to the sun is called an AU

How do bees help the decay process?

Answers

Bees help the decay process by aiding in the breakdown of organic materials through pollination. They transfer pollen from one flower to another, which is necessary for plant reproduction. This in turn helps to propagate the decaying process as new plants spread and die, bringing more organic materials into the decay cycle.

What is bee pollination?

Bees spread pollen between flowers, which is known as bee pollination. Pollen exchange results in fertilisation, which enables plants to develop seeds. A bee's diet is made up of floral nectar and pollen. Bees rely on pollen, a powdery, yellow material, as their main source of protein. Bees rely on nectar, a sweet, sugary liquid, for their source of carbohydrates. Buzz pollination is offered by some bee species. Buzz pollination is a method of pollination in which bees quickly vibrate their wings to induce pollen release from a bloom. In essence, they "shake" the pollen from the flower.

What is the process of decay?

The process of decay is a crucial part of the nutrition cycle because it converts dead organic matter into nutrients that other living things, typically plants, may utilise. An organism's body begins to disintegrate pretty quickly once it dies. Enzymes that break down proteins and other biological components in tissues are released by dead cells. In addition, creatures like worms, bacteria, and fungi arrive to aid in the breakdown of the organic components. Decomposers are the organisms that facilitate the breakdown process. They are categorised as saprotrophic because of how decaying bacteria and fungi break down dead organic molecules. They eat decaying stuff since they are unable to manufacture their own sustenance.

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What specific area on the body does the term axillary refer too?

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The term "axillary" specifically refers to the area of the body known as the armpit or underarm.

It is the space located beneath the shoulder joint where the upper arm meets the shoulder. The axilla is a small hollow or cavity formed by the junction of the upper arm and the lateral chest wall.

This region contains important structures such as lymph nodes, blood vessels, nerves, and sweat glands. The axillary region serves as a conduit for lymphatic drainage from the upper limb and plays a role in body temperature regulation due to the presence of sweat glands.

It is also a site commonly used for medical procedures, such as administering injections or measuring body temperature. Understanding the term "axillary" helps in accurately identifying and discussing anatomical landmarks and medical conditions related to this specific area of the body.

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How would the structure of a dicot root be affected if its main root structures werent there.

WILL GIVE BRAINLIIST

Answers

If the main root structures of a dicot plant are not present, the structure of its root system will be greatly affected.

What type of roots do Dicots have?

Dicots typically have a taproot system, which is characterized by a large, main root (the taproot) and smaller lateral roots branching off from it.

Without the taproot, the root system would likely be much less well-organized, with smaller lateral roots growing directly from the base of the stem. This could result in a less stable and less efficient root system.

Therefore, If the main root structures of a dicot plant are not present, the structure of its root system will be greatly affected.

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While science is generally firm in its conclusions, valid, new data regularly occurs; this forces scientists to re-evaluate or refine their hypotheses and theories. This best shows that science is:
replicable

flexible

fake

rigid

Answers

Answer:

replicable

Explanation:

becuase if science isn't replicable there isn't insufficient data.

•how can the use of hydroponics help increase the amount of food that can be grown on earth?​

patulong po pls

Answers

The use of hydroponics can increase the amount of food grown on Earth by providing a controlled environment for plant growth, optimizing resource utilization, and allowing for year-round production. This method eliminates the need for traditional soil-based farming and enables efficient and sustainable cultivation of crops.

Hydroponics is a soilless cultivation technique that involves growing plants in nutrient-rich water solutions. It offers several advantages that can help increase food production on Earth. Firstly, hydroponics allows for precise control over the growing conditions, including nutrient levels, pH, and water availability. This ensures that plants receive optimal nutrition and can grow more efficiently, leading to higher yields.

Secondly, hydroponic systems can be set up in vertical structures or compact spaces, maximizing land utilization. This is especially valuable in urban areas or regions with limited arable land, where traditional agriculture may be challenging. Furthermore, hydroponics enables year-round production since it is not reliant on seasonal changes or weather conditions. With artificial lighting and climate control, plants can be grown continuously, increasing the overall food supply and reducing dependence on specific growing seasons.

Additionally, hydroponics uses water more efficiently compared to traditional farming methods. The closed-loop systems recirculate water, minimizing water loss through evaporation or runoff. This is particularly beneficial in water-scarce regions, where conservation is crucial for sustainable agriculture. Overall, the use of hydroponics presents a promising solution to increase food production on Earth by optimizing resource utilization, enabling year-round cultivation, and minimizing environmental impact.

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describe the following Characteristics of Life display organization growth development requires energy reproduction respond to stimuli and maintains homeostasis​

Answers

Answer:

These characteristics of Life are very important.

Explanation:

Organization growth, development requires energy, reproduction respond to stimuli and maintains homeostasis​ are the characteristics of Life. These characteristics are very important for survival and for a good life. In the absence of these characteristics, the organisms will die. Energy is required for  the growth and development of an organisms. Equilibrium is maintained in the body of organism by maintaining homeostasis in the body which resist change in the body.

A homozygous recessive man has children with a heterozygous woman. 4. Give the genotype and phenotype of each parent. Genotype Phenotype Father Mother 5. Make a Punnett square of the cross described a

Answers

Genotype PhenotypeFather hh Homozygous recessive Mother Hh Heterozygous For the Punnett square of the cross described, the possible genotypes and phenotypes The following are the genotype and phenotype of each parent of a homozygous recessive man who has children with a heterozygous woman.

Genotype PhenotypeFather hh Homozygous recessive Mother Hh Heterozygous For the Punnett square of the cross described, the possible genotypes and phenotypes of their children can be calculated using the following steps:Step 1: Write the genotype of each parent along the top and left-hand side of the grid. Step 2: Place one allele from each parent in each box by drawing lines from the letters on the top to the letters on the left.

Step 3: Combine each pair of alleles to determine the genotype of the offspring in each box. Step 4: Determine the phenotype of each offspring based on their genotype.Based on the above information, the Punnett square of the cross between a homozygous recessive man and a heterozygous woman would be as shown below. From the Punnett square, it can be observed that the offspring would be 100% Hh (heterozygous). Therefore, their phenotype would be dominant (H).

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Which element is found in period 3, group 2? *

Answers

Answer:

Magnesium

Explanation:

Magnesium

Answer:

sodium, magnesium, aluminium, silicon, phosphorus, sulfur, chlorine, and argon.

Explanation:

The third period contains eight elements: sodium, magnesium, aluminium, silicon, phosphorus, sulfur, chlorine, and argon. The first two, sodium and magnesium, are members of the s-block of the periodic table, while the others are members of the p-block.

sydney had an infection 10 years ago that left scarring in her uterine tubes. due to this scarring, the diameter of the uterine tubes has been reduced by 75%. what effects may sydney experience? question 6 options: endometrium may not mature as needed for implantation. the cervix may not dilate during birth. during pregnancy the fetus may not mature to full size. oocytes may not reach the uterus.

Answers

Sydney, who has scarring in her uterine tubes resulting in a 75% reduction in diameter, may experience various effects, including a potential hindrance in the maturation of the endometrium, difficulties in cervical dilation during childbirth and potential challenges in fetal development.

The uterine tubes, also known as fallopian tubes, play a crucial role in female reproductive health. They provide a pathway for oocytes (eggs) to travel from the ovaries to the uterus, where fertilization and implantation occur. The scarring in Sydney's uterine tubes, causing a significant reduction in diameter, can have several effects.

Firstly, the reduced diameter of the uterine tubes may hinder the passage of oocytes from the ovaries to the uterus. This can make it difficult for fertilization to occur, impacting Sydney's ability to conceive.

Secondly, the scarring may interfere with the normal maturation of the endometrium, the lining of the uterus. This can affect the implantation of a fertilized egg and potentially lead to difficulties in establishing and maintaining a pregnancy.

Furthermore, during childbirth, the reduced diameter of the uterine tubes may contribute to challenges in cervical dilation, which is necessary for the safe delivery of the baby.

Lastly, the scarring in the uterine tubes may also affect the growth and development of the fetus during pregnancy, potentially leading to suboptimal fetal size or growth restriction.

It is important for Sydney to consult with a healthcare professional or fertility specialist to explore the specific implications of her condition and discuss potential treatment options or interventions to address any fertility or pregnancy-related challenges she may face.

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A given bacteria culture initially contains 1500 bacteria and doubles every half hour. The number of bacteria p at a given time t (in minutes) is given by the formula p(t)=1500e^(kt) for some constant k. (You will need to find k to answer the following.)
a) Find the size of the bacterial population after 110 minutes.
b) Find the size of the bacterial population after 8 hours​

Answers

the size of the bacterial population after 8 hours is 1,228,800.

a) The size of the bacterial population after 110 minutes is 48,000.

To find the size of the bacterial population after 110 minutes, we must first find the value of k.

Since the bacteria doubles every half hour, it will multiply by a factor of 2 every 30 minutes or every 0.5 hours.

So, we can use this information to find the value of k as follows:

1500e^(kt) = 2(1500e^(k(t-0.5)))

We can cancel out the 1500 on both sides of the equation to get:

e^(kt) = 2e^(k(t-0.5))

Taking the natural logarithm of both sides gives:

kt = ln(2) + k(t-0.5)

Simplifying this equation gives:

k = ln(2)/0.5 = 1.3863

Substituting this value of k into the formula for p(t) gives:

p(t) = 1500e^(1.3863t)

So, the size of the bacterial population after 110 minutes is:

p(110) = 1500e^(1.3863(110)) = 48,000 (rounded to the nearest whole number).

b) The size of the bacterial population after 8 hours is 1,228,800.

We know that 8 hours is equal to 480 minutes, so we can use the formula:

p(t) = 1500e^(1.3863t)

to find the size of the bacterial population after 8 hours as follows:

p(480) = 1500e^(1.3863(480)) = 1,228,800 (rounded to the nearest whole number).

Therefore, the size of the bacterial population after 8 hours is 1,228,800.

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50 points

Which of the following is not a characteristic of a living thing?
A. All living things grow and change over time.
B. All living things use gasoline to metabolize energy.
C. All living things interact with their environment.
D. All living things have the ability to reproduce.

Answers

Answer:

I believe your answer should be B. All living things use gasoline to metabolize energy.

Explanation: Living things don't need gasoline for energy.

Hows my physique looking?
Im 15 years old, ive been consistently going to the gym for 7 months now, and im completely natty (not even creatine)

Hows my physique looking?Im 15 years old, ive been consistently going to the gym for 7 months now, and

Answers

Answer:

7 MONTHS?! Bro that's a lot

Explanation:

The brain is in which part of the nervous system?
A. Peripheral
B. Central
C. Autonomic
D. Sensory

Answers

Answer: B. Central nervous system

Answer is B! Hope this will work!

whats the answerrrrrrr

whats the answerrrrrrr

Answers

Explanation:

The germ theory of disease is the currently accepted scientific theory for many diseases. It states that microorganisms known as pathogens or "germs" can lead to disease. These small organisms, too small to be seen without magnification, invade humans, other animals, and other living hosts. Their growth and reproduction within their hosts can cause disease ¹.

Based on this information, it seems that option C: "one infectious agent causes one disease" is the closest to the germ theory of disease.

explain how temperature affects population size​

Answers

Answer: High temperature and drying were both associated with greater per capita mortality rate. Smaller population sizes at high temperatures and drying regimes may result from increased desiccation of adults and thus higher mortality. These precipitation effects on adult production are absent at 22°C

OR

Other than toxic metals, temperature rise and low resource availability are factors that are also known to stress populations. A rise in temperature generally accelerates metabolic rates and hence population growth rate

Pig dissection circulatory system terms and functions

Answers

Here are terms and functions of the pig circulatory system:

Arteries: Arteries are blood vessels that carry blood away from the heart.Capillaries: Capillaries are very small blood vessels that allow the exchange of oxygen and nutrients between the blood and the cells.Heart: The heart is a muscular organ that pumps blood throughout the body.Lungs: The lungs are organs that allow the exchange of oxygen and carbon dioxide in the blood.Veins: Veins are blood vessels that carry blood back to the heart.

What does the circulatory system do?

The circulatory system of a pig is similar to that of a human. It is made up of the heart, blood vessels, and blood. The heart is a muscular organ that pumps blood throughout the body. The blood vessels are tubes that carry blood to and from the heart. The blood is a fluid that contains red blood cells, white blood cells, and platelets.

During a pig dissection, the circulatory system consists of various structures that play essential roles in the transportation of oxygen, nutrients, and waste throughout the body.

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A plant living in a dry area will likely have a substance that helps to minimize water loss from the leaves. What is that substance ?

Answers

Answer:

stomata is the substance that helps to minimize water loss.

The plant wax will surely helps this organism to minimize water loss from all its leaves.

What is the plant wax?

The plant wax is a compound composed of different chemical substances (e.g., hydrocarbons, alcohols, ketones, etc).

The wax is generally found in a layer that is outside epidermal plant cells.

In conclusion, the plant wax will surely helps this organism to minimize water loss from its leaves.

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pls help!!
The following tracking model was created for Hurricane Ike on September 8, 2008. ^^
According to this model, at which point is the storm least likely to make landfall?
1) Point A
2) Point B
3) Point C
4) Point D​

pls help!!The following tracking model was created for Hurricane Ike on September 8, 2008. ^^According

Answers

Answer:

Its Point A

Explanation:

The following tracking model was created for Hurricane Ike on September 8, 2008. Map of Gulf Coast showing the forecasted path of Hurricane Ike on September 8, 2008. The storm’s current location, as of 5 p.m. on Friday, is just south of Cuba, over the Caribbean Sea. The “cone of probability” extends northwest. Point A is located along the Texas coast, right in the center of the cone’s widest point. Point B is located along the coast of Louisiana, toward the easternmost edge of the cone. Point C is located further east, along the coast of the Florida Panhandle. Point D is located on the border between Mexico and Texas, toward the southwestern-most edge of the cone. According to this model, at which point is the storm least likely to make landfall?

Ingest foreign particles or bacteria that the neutrophils are unable to digest.

Answers

"Phagocytosis" is the medical word for ingestion foreign particles or germs that neutrophils are unable to process. The buildup of these particles or bacteria can result in the creation of an abscess or other forms of inflammatory reaction when the neutrophils are unable to breakdown the ingested material.

An essential function of the immune system is phagocytosis. The immune system uses a variety of cells, including neutrophils, macrophages, dendritic cells, and B lymphocytes, to carry out phagocytosis.

Immune system cells can identify the pathogens or foreign objects they are battling by phagocytosing them. The neutrophils' ability to kill microbes relies heavily on phagocytosis. Pathogens are initially taken up by the phagosome, a plasma membrane-derived vacuole that continues to grow.

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Correct Question:

What is the medical term for ingest foreign particles or bacteria that the neutrophils are unable to digest?

A 6.4 KD protein is digested with trypsin to generate fragments with masses of 666 Da, 721 Da, 759 Da, 844 Da, 912 Da, 1028 Da and 1486 Da. a. Draw an SDS-PAGE of the peptides and label each band with the appropriate mass. Be sure to include a standard ladder on your gel.

Answers

The SDS-PAGE gel would show bands corresponding to the digested protein fragments with masses of 666 Da, 721 Da, 759 Da, 844 Da, 912 Da, 1028 Da, and 1486 Da. A standard ladder should be included for reference.

SDS-PAGE (Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis) is a common technique used to separate proteins based on their molecular weight. In this case, the 6.4 KD (kilodalton) protein has been digested with trypsin, an enzyme that cleaves proteins at specific sites. The resulting fragments have different masses, which can be visualized on an SDS-PAGE gel.

The gel would consist of a polyacrylamide matrix through which an electric field is applied. The negatively charged SDS molecules bind to the proteins, causing them to unfold and acquire a negative charge proportional to their size. As a result, the proteins migrate towards the positive electrode during electrophoresis, with smaller proteins moving faster and migrating farther through the gel.

By running the digested protein fragments alongside a protein standard ladder, which contains proteins of known molecular weights, we can estimate the size of the fragments based on their migration distance. Each fragment would appear as a distinct band on the gel, and the position of the band relative to the ladder can be used to determine its molecular weight.

In this case, the gel would show bands corresponding to the fragments with masses of 666 Da, 721 Da, 759 Da, 844 Da, 912 Da, 1028 Da, and 1486 Da. The ladder bands would serve as reference points, allowing us to assign the appropriate mass to each fragment band.

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Which phrase correctly identifies one way that veins function in the circulatory system?
Blood is carried under high pressure in veins.
Gas exchange takes place over the thick walls of veins.
Blood is prevented from backflow by valves in veins.
Nutrient exchange takes place over the thin walls of veins.
Veins carry blood back to the heart--often against the pull of gravity.

Answers

It’s E. Veins carry blood back to the heart often against the pull of gravity

Answer:

Blood is prevented from backflow by valves in veins.

Explanation:

suppose your cells continue to help heal the scrape that resulted from the falling off your bike.what might happen if the cell cycle did not go into a rest phase explain.​

Answers

Answer:

If the cell cycle did not go into a rest phase, what would occur would be uncontrolled cell growth. This could lead to tumor formation and cancer.

When the cell cycle fails to go into a rest phase than formation of tumor or cancer may take place.  

• Generally, the cells in humans grow and proliferate to produce new cells as the body requires then. In case, when the cells become damaged or become old, they perish, and formation of novel cells takes place.  

• However, the order may break, and the damaged or abnormal cells grow and proliferate when they should not, that is, the cells fails to go into the resting phase.  

• These cells may give rise to formation of tumors, that is, the lumps of tissue, these tumors can be non-cancerous, that is, benign or can be cancerous, that is, malign.  

Thus, the cells when failing to go into the resting phase may turn into tumors or cancerous cells.

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A city is powered by energy from coal. the city incorporates the use of biofuels from existing corn crops as an alternate source of energy.

what can be an environmental impact of this change?

a. decrease in biodiversity
b. increase in pollution
c. decrease in carbon emissions
d. increase in surface temperatures

Answers

An environmental impact of a city switching from coal to biofuels from existing corn crops as an alternate source of energy can be a decrease in carbon emissions (option c).

When a city switches from using coal as its primary energy source to using biofuels from existing corn crops, it is effectively transitioning from a fossil fuel to a renewable energy source.

Coal, a fossil fuel, releases a large amount of carbon dioxide (CO2) and other harmful pollutants when it is burned to produce energy. These carbon emissions contribute to global warming and air pollution. On the other hand, biofuels, such as those derived from corn crops, produce significantly fewer CO2 emissions compared to coal.

This is because biofuels are derived from plants, which absorb CO2 from the atmosphere during their growth. As a result, the overall CO2 emissions are reduced when biofuels are used as an alternative energy source.

In summary, when a city incorporates the use of biofuels from existing corn crops as an alternate source of energy, it leads to a decrease in carbon emissions. This change can have positive impacts on the environment, such as reduced air pollution and mitigation of global warming.

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Amino acid is to a protein as

1. Fat is to a lipid
2. DNA is to RNA
3. Sugar is to fat
4. Nucleotide is to nucleic acid

Answers

Answer: A) Fat is to a lipid.

Explanation:

How can AKT1 gene enhance athletic performance?

Answers

Answer:

It gives instrucions or orders to make proteins called AKT1 kinase.

Explanation:

That specific protein is found in various cell types all through the body. It plays a big role in signaling pathways.

Hope this helps :)

The specific protein is found in variable cells which is to be caused by the proteins in the blood stream.

which event is mostly responsible for increasing the opportunity for animals to develop more complex traits?
A. increase in genetic material (DNA)
B. jaws
C. bilateral symmetry
D. spinal column

Answers

Increase in genetic material (DNA) event is mostly responsible for increasing the opportunity for animals to develop more complex traits. The correct answer is option A.

The evolution of life on earth is marked by an increase in the amount of genetic material in living organisms. This increase in genetic material has enabled animals to develop more complex traits and adapt to a wider range of environments.

The gradual accumulation of genetic changes over time, as well as the movement of organisms into new environments, has led to the emergence of new species with unique physical and behavioral characteristics.

In many cases, these new species have been able to survive and thrive in their new environments because of the complex traits they possess, which allow them to compete for resources and avoid predators more effectively.

The correct answer is option A.

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If a sperm cell were produced by mitosis rather than meiosis, the offspring receiving that sperm cell most likely would:

A. grow larger because it had extra chromosomes.

B. have fewer chromosomes than either of its parents.

C. grow poorly with an incorrect number of chromosomes.

D. have more chromosomes than either of its parents.

Answers

Answer:

d

Explanation:

i took the test

The enzyme changes the substrate to create a _______.

Answers

Answer: an enzyme products complex.

Explanation:

To catalyze a reaction, an enzyme will grab on (bind) to one or more reactant molecules. These molecules are the enzyme's substrates. This forms the enzyme-substrate complex. The reaction then occurs, converting the substrate into products and forming an enzyme products complex.

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Pls help Ill brainlest and add extra pointsJust do number 1 what is the difference between internal and external growth? Please explain? HELP ME PLEASE ASAP! Function f is defined by the equationf(x)=ax + [tex]\frac{2}{a} x[/tex]. If f(3) f(2) = 11, what is thesmallest possible value of a? Which student was practicing poor laboratory safety?Gunther read all the safety precautions for an experiment and collected his chemicals.Herbert started mixing his chemicals as the teacher began explaining the lesson.Francine washed her hands after spilling table salt on them.Reilly tied her hair back into a ponytail after putting on her lab coat. Archaeologists Louis and Mary Leakey found some of the oldest human remains in __________ during the 1950s.A.South AfricaB.BolgatangaC.the Kalahari DesertD.Olduvai Gorge 100 students are interviewed to see which of biology, chemistry or physics they prefer. 29 of the students are girls. 9 of the girls like biology best. 20 of the boys prefer physics. 9 out of the 27 who prefer chemistry are girls. What percentage of the students prefer biology?Help would be highly appreciated! Which layer of the atmosphere contains the ozone layer?A. StratosphereB. TroposphereC. ExosphereD. Mesosphere v be the waves speed A its wavelength and f its frequency These quantities are related via the equation v = lambda if the wave speed decreases, the wavelength must also decrease for the frequency to remain constant What is the wavelength lambda of light in glass, if its wavelength in air is lambda_0, its speed in the glass? Express your answer In terms of lambda_a, c, and v. The index of refraction n for a material is defined to be n = c/v Rewrite your answer from Part A in terms of the refraction Express your answer In terms of lambda_n and n. Determine the pH of 1 x 10^-2 the NaOH.a. 2.0b. 4.0c. 8.0d. 12.0 which of the following statements about the byzantine empire is true PLEASE HELP ASAP BRAINLIEST Easy Q Peer CounselingWhat is one thing you wished more people understood about you?pls and thx Describe 19th century European nationalism? Who were thesenationalists and what were their ultimate aims? use the gcf and the distributive property to find the sum of 26 + 39 Find the coordinates of the vertices of the figure after the giver transformation: T true or false issuers of securities offerings must comply with either federal or state securities laws, but not both. 7. Expresar en notacin cientfica las siguientescantidades:A. 89500000000 mm taylor wants to gain additional information about the people using their website in an unobtrusive way and incorporate analytics. to do this, they can... What is the 14th partial sum of 2,000 1,000 + 500 250 + ...? Round your answer to the thousandths place.1,333.2521,333.3331,999.8783,999.756