Which of the following regulate oxidative phosphorylation under hypoxic conditions?

Pyruvate dehydrogenase (PDH) kinase phosphorylates PDH, inactivating it and reducing the availability of electron carriers to the electron transport chain.

I decreases below 6.5 and IF1 exists as a stable dimer capable of inhibiting the ATPase activity of ATP synthase.

ATP synthase converts ATP to ADP, raising [ADP] to increase the rate of oxidative phosphorylation.

HIF-1 replaces a subunit of Complex IV of the electron transport chain with a subunit that is more efficient under hypoxic conditions.

The protein inhibitor IF1 binds one ATP synthase molecule and inhibits its activity.

Answers

Answer 1

Under hypoxic conditions, the regulation of oxidative phosphorylation involves the following processes, Pyruvate dehydrogenase (PDH) kinase phosphorylates PDH, inactivating it and reducing the availability of electron carriers to the electron transport chain. IF1, an inhibitor of ATP synthase, exists as a stable dimer and inhibits the ATPase activity of ATP synthase when the pH decreases below 6.5. ATP synthase converts ATP to ADP, increasing the concentration of ADP and thereby enhancing the rate of oxidative phosphorylation.

Under hypoxic conditions (low oxygen), the regulation of oxidative phosphorylation is necessary to maintain energy production. One mechanism involves the phosphorylation of pyruvate dehydrogenase (PDH) by PDH kinase. PDH normally converts pyruvate into acetyl-CoA, which enters the citric acid cycle to generate electron carriers (NADH and FADH₂) for the electron transport chain. Phosphorylation of PDH by PDH kinase inactivates PDH, reducing the availability of electron carriers and consequently limiting oxidative phosphorylation.

Another regulatory mechanism involves the protein inhibitor IF1. When the pH decreases below 6.5, IF1 exists as a stable dimer, allowing it to bind to ATP synthase. ATP synthase is responsible for converting ADP and inorganic phosphate (Pi) into ATP during oxidative phosphorylation. By inhibiting the ATPase activity of ATP synthase, IF1 reduces the production of ATP, thereby regulating the energy output under hypoxic conditions.

Additionally, under hypoxic conditions, the concentration of ADP increases due to limited ATP production. This rise in ADP levels stimulates the rate of oxidative phosphorylation. As ADP is converted into ATP by ATP synthase, the increased concentration of ADP drives the production of ATP to meet the energy demands of the cell.

In summary, under hypoxic conditions, the regulation of oxidative phosphorylation involves the inactivation of PDH, the inhibitory action of IF1 on ATP synthase, and the increase in ADP concentration to enhance ATP production.

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Related Questions

what structural elements enable the distention of the urinary bladder?

Answers

The structural elements that enable the distension of the urinary bladder are transitional epithelium and smooth muscle fibers.

The urinary bladder is a hollow, muscular organ that stores urine until it is ready to be expelled from the body. The bladder can distend, or expand, to accommodate increasing amounts of urine due to its unique structural elements. The inner lining of the bladder is composed of transitional epithelium, which can stretch and fold without tearing as the bladder expands.

The bladder is also surrounded by layers of smooth muscle fibers, which can contract to expel urine from the bladder. These structural elements work together to allow the bladder to distend and function properly in the urinary system.

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How do DNA and RNA differ?

Answers

Answer:

DNA is a long polymer with deoxyriboses and phosphate backbone. Having four different nitrogenous bases: adenine, guanine, cytosine and thymine. RNA is a polymer with a ribose and phosphate backbone. Four different nitrogenous bases: adenine, guanine, cytosine, and uracil.

Answer:

DNA contains the sugar deoxyribose, while RNA contains the sugar ribose. DNA is a double-stranded molecule, while RNA is a single-stranded molecule. DNA is stable under alkaline conditions, while RNA is not stable. DNA and RNA perform different functions in humans.

Explanation:

How do DNA and RNA differ?

Which radioactive element is best suited for determining age of wooden tools used by prehistoric humans during the last ice age?

Answers

Carbon-14 is the radioactive element which will be best suited for determining the age of the wooden tools which were used by the prehistoric humans during the last ice age.

Radiocarbon dating which is also referred as carbon dating or the carbon-14 dating is a method which is used for the determination of the age of a particular object which contains the organic material by utilizing the different properties of the radiocarbon which basically a radioactive isotope of carbon.

Over time this carbon-14 happens to decay in predictable ways. With the help of the radiocarbon dating researchers can use this decay like a clock which allows these scientist to look into the past and be able to determine the absolute dates of everything ranging from wood to food, poop, pollen, and even dead animals and humans.

Therefore, carbon-14 dating can be used for determining the age of the wooden tools which were used by the prehistoric humans during the last ice age.

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In an experiment, Charles Darwin's prediction about long nectaries and long-tongued moths would be a(n)

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In an experiment, Charles Darwin's prediction about long nectaries and long-tongued moths would be a hypothesis.

English scientist, geologist, and biologist Charles Robert Darwin FRS FRGS FLS FZS JP (12 February 1809 – 19 April 1882) is well recognised for his contributions to evolutionary biology. His theory that all living things have a common ancestry is now widely recognised and regarded as a fundamental idea in science. He presented his scientific idea that this branching pattern of evolution was the product of a process he called natural selection, in which the battle for existence has a comparable impact as the artificial selection involved in selective breeding. This theory was first published in a collaborative work with Alfred Russel Wallace.

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What is the diameter of a capillary tube in which mercury?

Answers

The diameter of a capillary tube is 2.5135m

What is capillary tube?

Capillary tubes are those with very small diameters (narrow cylindrical tubes). When these small tubes are immersed in a liquid, the liquid in the capillary either rises (or lowers) relative to the surrounding liquid level. This phenomenon is known as capillary action, and such tubes are known as capillary tubes.

Rise in capillary is given by

h = \(\frac{2\times \sigma \times cos\theta}{\rho \times r\times g}\)

σ = surface tension

ρ = density of liquid

r = inner radius

h = height

θ = contact angle made by the liquid meniscus with the capillary’s surface.

Given,

h = 1.21 cm

σ = 540 × 10 N/m

θ = 140°

ρ = 13.6 × 10³ Km

Substituting the value in equation,

h = \(\frac{2\times \sigma \times cos\theta}{\rho \times r\times g}\)

r = \(\frac{2\times 540\times10\times cos140}{13.6\times10^3\times1.21\times10^-^2\times10}\)

r = 50.27 × 10⁻¹m

d = 2.5135m

The diameter of a capillary tube is 2.5135 m.

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I think it might be organ system but I’m not sure

I think it might be organ system but Im not sure

Answers

It’s not an organ because it’s a plant so it would be a cell

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Lysosomal storage diseases (LSDs) are a group of rare and inherited genetic disorders in which some part of the lysosome does not function properly, causing the accumulation of toxic substances in the cell and ultimately, cell death.

What would be the most likely explanation as to why the lysosomes of someone with this disease are not functioning properly?

Choose 1 answer:

(Choice A)
A
The enzymes of the lysosome are not breaking down enough toxic material.

(Choice B)
B
The enzymes of the lysosome are beginning to break down the ribosomes of the cell.

(Choice C)
C
The enzymes of the lysosome are breaking down too much toxic material.

(Choice D)
D
The enzymes of the lysosome are beginning to break down the DNA of the cell.

Answers

Answer: The enzymes of the lysosome are not breaking down enough toxic material

Explanation:

Leaf type is a characteristic that is often used in dichotomous keys to help identify plants. Click on the letter that represents a compound leaf type.

Someone please help it's due today!!!!

Leaf type is a characteristic that is often used in dichotomous keys to help identify plants. Click on

Answers

By using leaf type as a characteristic in a dichotomous key, it is possible to distinguish between different plant species based on the arrangement and structure of their leaves.

What is Dichotomous?

"Dichotomous" refers to a division into two distinct parts or categories. It is often used to describe a classification system that separates things or concepts into two mutually exclusive groups. For example, in biology, a dichotomous key is a tool used to identify organisms based on a series of binary choices that lead to the correct identification. In psychology, a dichotomous variable is a variable that can take on only two values, such as "male" or "female." The word "dichotomy" comes from the Greek word "dichotomia," which means "cutting in two."

The letter that represents a compound leaf type in a dichotomous key is usually "B". Compound leaves are leaves that are divided into multiple leaflets, each of which is attached to a central stem called the rachis. Each leaflet may have its own stalk, known as the petiolule, that connects it to the rachis. In contrast, simple leaves have only one blade attached to the petiole.

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What is the cellular system

Answers

Answer:

A cellphone network. Often spanning an entire country, a cellular system comprises a core network that connects to base stations with antennas on towers that span up to 20 miles in diameter. GSM and CDMA are the two major cellular technologies.

Explanation:

Answer:

Often spanning an entire country, a cellular system comprises a core network that connects to base stations with antennas on towers that span up to 20 miles in diameter. GSM and CDMA are the two major cellular technologies. See cellphone, cellular generations, GSM, CDMA and microcell.

Explanation:

got it from goo gle

Diagrams,tables,and graphs are used by scientists mainly to

Answers

to show data

Explanation:

Scientists uses Graphs, Diagrams and Tables as visual to show relationships between data and are intended to display the data in a way that is easy to understand and remember. People often use graphs and charts to demonstrate trends, patterns and relationships between sets of data.

A wave has a frequency of 50 Hz and a wavelength of 10 m. What is the speed of the wave?

Answers

Answer:

500 m/s

Explanation:

Velocity (v) = wavelength (λ) x frequency (f)

V = 10 x 50

V = 500 m/s

The _____ is a major neuroendocrine pathway that activates sympathetic neurons which then tell the adrenal gland to release norepinephrine.

Answers

The hypothalamic-pituitary-adrenal (HPA) axis is a major neuroendocrine pathway that activates sympathetic neurons, which then tell the adrenal gland to release norepinephrine.

What is the hypothalamic-pituitary-adrenal (HPA) axis?

The hypothalamic-pituitary-adrenal (HPA) axis is a complex interrelationship between the hypothalamus, the pituitary gland, and the adrenal gland. These three glands work together to regulate the body's stress response system. The hypothalamus produces corticotrophin-releasing hormone (CRH), which stimulates the pituitary gland to release adrenocorticotropic hormone (ACTH).

This hormone then activates the adrenal gland to produce and release cortisol and other stress hormones such as adrenaline and noradrenaline. These hormones help the body to respond to stress and protect itself from harm. However, prolonged activation of the HPA axis can lead to negative health consequences such as anxiety, depression, and immune system dysfunction.

In summary, the hypothalamic-pituitary-adrenal (HPA) axis is a major neuroendocrine pathway that activates sympathetic neurons, which then tell the adrenal gland to release norepinephrine.

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What are S-strain and R-strain bacteria?

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Answer:

When Frederick Griffith discovered two strains of Streptococci in 1923, the bacteriologists were intrigued by the differences between them: the S (smooth) strain, which produces colonies that are smooth and shiny on a lab plate; the R (rough) strain, which lacks a polysaccharide coat and produces colonies that are rough and irregular on a lab plate.

Explanation:

which of the following is a medical complication normally associated with bulimia nervosa? question 9 options: shrinking of the heart osteoporosis kidney failure stress fractures lanugo

Answers

The following is a medical complication normally associated with bulimia nervosa shrinking of the heart osteoporosis kidney failure stress fractures lanugo.

Bulimia nervosa, also called bulimia, is an eating disorder. eating problems are mental fitness situations that may be probably life-threatening. when you have an ingesting disorder, you could have an obsession with meals and weight. This obsession can harm your bodily and emotional nicely-being.

Bulimia nervosa, frequently known as bulimia, is a sort of eating disorder. human beings with bulimia eat big amounts of food at one time, then attempt to dispose of the food or weight benefit by way of throwing up, taking laxatives, fasting (now not eating anything), or workout lots greater than ordinary.

Bulimia can permanently damage your stomach and intestines, causing other troubles like constipation, diarrhea, and irritable bowel syndrome. Hormonal troubles. Reproductive problems, together with abnormal durations, overlooked periods, and fertility problems are not unusual aspect outcomes if you have bulimia.

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a single bacterium has epitope(s). True or false?

Answers

A single bacterium has epitope(s) are false

A single bacterium has multiple epitopes.

An epitope, also called an antigenic determinant, is the part of an antigen that is recognized by the immune system, especially antibodies, B cells, or T cells. The portion of an antibody that binds to an epitope is called the paratope. An epitope is a portion of an antigen that the host's immune system recognizes and elicits an immune response against invading pathogens. It binds specifically to the corresponding antigen receptor on immune cells (such as B cells) and only binds when the structures are complementary.

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IN YOUR OWN WORDS, what are the definitions for Interkinesis (include when it happens)?

Answers

INTERKINESIS:

Interkinesis is also known as interphase II that occurs during meiosis, between meiosis I and meiosis II.

No DNA replication takes place during this phase.

Specifically in plants when two daughter cells are produce by the process of meiosis I, immediately they prepare for meiosis II.

During this period nuclear envelope begin to appear for temporary, which is known as interkinesis that helps in the separation of two sets of chromosomes.

coarse sand can absorb a great deal of water during a rain, but what happens to the water soon after the rain stops? what would happen instead if the soil consisted of clay micelles?

Answers

If the soil instead consisted of clay micelles, the water-holding capacity would be much higher due to the small particle size and high surface area of the clay.

Coarse sand can absorb more than 100 times its own weight in water during a rain event. However, this water is not retained for long because the large pore spaces between the sand grains allow for rapid drainage and little water retention. As a result, the water quickly percolates downward through the soil profile and is lost from the system.
The water would be held in the soil for longer periods of time, allowing for more efficient uptake by plants and reduced runoff. However, clay soils also have a greater potential for compaction and waterlogging, which can negatively impact plant growth.

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What is the most common molecule in living things? A. CO B. He с. А,о D. CO​

Answers

Answer:

proteins

Explanation:

Please answer asap I'll give brainlist to the correct answer​

Please answer asap I'll give brainlist to the correct answer

Answers

This isn't as complicated as it looks.

1. If you have 10% solute, then you have 90% solvent because 90% + 10% = 100%..

2. If you have 20% solute, then you have 80% solvent because 80% + 20% = 100%.

3. The cell is hypotonic compared to the beaker because it has less solute inside of it. Usually people say the solution's tonicity and not the cell's tonicity though.

4. Because the cell has less solute than its environment, water will flow outside of the cell. Think of it as water flowing outside to "dilute" more concentrated areas. Water always flows from an area of low concentration to an area of high concentration to achieve equilibrium.

magnesium’s major functions in the body include all of the following except: group of answer choices blood clotting. being a cofactor for many enzymes. stabilizing atp. maintenance of bones.

Answers

Magnesium’s major functions in the body include all of the following except blood clotting. Magnesium plays a vital role in many biological processes in the body.

It is essential for maintaining strong bones and healthy muscle function, as well as for the transmission of nerve impulses, maintaining a healthy immune system, and regulating heart rhythm.Magnesium is also a cofactor for many enzymes and plays a crucial role in stabilizing ATP, the energy currency of the body. However, magnesium does not play a role in blood clotting. Blood clotting is a complex process involving different proteins and platelets.

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What is the job of proteins in the plasma membrane?

Answers

Answer:

distribution of drugs

Explanation:

Proteins in the cell membrane play a role in many other functions, such as cell signaling, cell recognition, and enzyme activity. Carbohydrates. Carbohydrates are also found in the plasma membrane; specifically, most carbohydrates in the membrane are part of glycoproteins, which are formed when a carbohydrate attaches to a protein.

Answer:

Transport nutrients

Explanation:

For example, plasma membrane proteins carry out functions as diverse as ferrying nutrients across the plasma membrane, receiving chemical signals from outside the cell, translating chemical signals into intracellular action, and sometimes anchoring the cell in a particular location

what is another name for the polymers of carbohydrates?

Answers

Answer:

polysaccharide

Explanation:

You are a NASCAR race car driver/pit crew member. You need to make sure that the tires on your car are running as efficiently as possible. What factors (in terms of Gas laws) do you need to take into consideration when trying to make sure your tires do not blow out? What gas law(s) applies to this situation?

Answers

As a NASCAR race car driver/pit crew member, several factors related to gas laws need to be considered to ensure the efficient functioning of tires and prevent blowouts. The relevant gas law for this situation is the ideal gas law, which includes variables such as pressure, volume, temperature, and the number of gas molecules.

When it comes to tire efficiency and preventing blowouts, the ideal gas law is applicable. The ideal gas law states that the pressure (P) of a gas is directly proportional to its temperature (T), and inversely proportional to its volume (V), when the number of gas molecules (n) remains constant. This means that maintaining optimal pressure and temperature in the tires is crucial to prevent blowouts.

Factors to consider include:

Pressure: The tires should be inflated to the recommended pressure level to ensure proper contact with the road surface and prevent overinflation or underinflation, which can lead to increased risks of blowouts.Temperature: Heat affects tire pressure, and as the temperature increases, so does the pressure inside the tires. Monitoring and adjusting tire pressure according to temperature changes is important for maintaining stability and avoiding blowouts.Volume: The volume of the tire remains constant unless changes are made to the tire itself. Proper tire maintenance, including regular inspections for any structural damage or wear, is crucial for preventing blowouts.

By carefully considering these factors and applying the principles of the ideal gas law, race car drivers and pit crew members can optimize tire performance, ensure efficient running, and minimize the risk of tire blowouts during high-speed races.

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The diagram shows a plant cell and an
animal cell. Which is most likely true about
both cells?

The diagram shows a plant cell and ananimal cell. Which is most likely true aboutboth cells?

Answers

Animal and plant cells have many differences concerning their structure. However they also chare some characteristics, like having mitochondria. B is correct. Both cells use the same molecules fro energy.

What are the differences between animal and plant cells?

Both animal and plant cells are eukaryotic. They carry their genetic material in the nucleus and mitochondria. Organelles are located in the cytosol, and both of them are surrounded by a cell membrane.

However, they have some differences:

Cell wall: A rigid structure that provides support and protection.

- Animal cells do not have a cell wall. They are only surrounded by the cell membrane, which is flexible so they can adopt different shapes.

- Plant cells have a wall, so their shape is usually prismatic and regular. The cell wall is composed mainly of cellulose.

Chloroplast: these are organelles that accumulate chlorophyll.

- Animal cells do not have chloroplasts because they do not photosynthesize.

- Plant cells have chloroplasts, and they are in charge of the photosynthesis process that allows plants to release oxygen. These organelles use solar light as a source of energy.

Vacuoles:

- Animal cells have many small vacuoles whose function is to store water, ions, and waste intracellular substances.

- Plant cells have a unique big-sized vacuole that might occupy almost 90% of the cell. Their principal function is to store water and keep the turgidity. When the vacuole gets empty, the plant loses rigidity.

Other differences are:

- The animal cell has centrioles, while the vegetable cell does not.

- Plasmodium, chromoplasts, and glyoxysomes are present in the vegetable cell but not in the animal cell.

Option B is correct. Both cells use the same molecules fro energy.

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If you are a healthy father to hemophilia and a carrier mother:
A. Specify the genotype of the parents.
B. What is the new genotype and phenotype expected in the child?​

Answers

Answer:

both

Explanation:

If you don't know how to set up a Punnett Square, what are you ... What is the probability this client is heterozygous? a) zero b) 0.25 ... Both parents are healthy. This tells you, if the kid with the disease is hh that each parent gave a little h. ... What is the most probable genotype for the parents of a child who ...

1 The variation of coat color in rodents is an example of ?

A. genetic diversity
B. asexual reproduction
C. individual effort
D. increased chances for survival

Answers

Answer:

A

Explanation:

Different genes exist

In terms of the carbon cycle explain why deforestation in the Amazon
is a global concern and not just a regional concern for the Brazilians.

Answers

Photosynthesis is the only was Carbon Dioxide is removed from the atmosphere. Less trees means less photosynthesis taking CO2 out of the atmosphere. This means there will be too much CO2, causing global warming (since CO2 is a greenhouse gas)

Deforestation in the Amazon is a global concern and not just a regional

concern for the Brazilians because of the large and diverse ecosystem

comprising of a lot of plant and animal species found in this rainforest.

The deforestation of trees in the Amazon will have a negative impact on the

earth as a result of accumulated carbondioxide being present in the

atmosphere.

This carbondioxide accumulation which is meant to be used by plants for

photosynthesis will then result to global warming .

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What was the name of the cyclone that hit Chandipur in 2009?

Answers

Answer:

The name of cyclone that hit chandipur in 2009 was tropical cyclone.

which cytoskeleton component plays a major role in the formation of the mitotic spindle?
a. intermediate
b. filaments
c. microfilaments
d. microtubules

Answers

Microtubules play a major role in the formation of the mitotic spindle during cell division. The correct answer is (d ) microtubules

The mitotic spindle is a dynamic structure composed of microtubules that forms during mitosis and is responsible for separating the duplicated chromosomes into two daughter cells.Microtubules are hollow tubular structures made up of tubulin protein subunits. They form the framework of the mitotic spindle and are involved in capturing and organizing the chromosomes, as well as facilitating their movement during cell division.

Other components of the cytoskeleton, such as intermediate filaments and microfilaments, have important roles in cellular structure and function but are not primarily involved in the formation of the mitotic spindle.

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select all of the following that describe active transport
A at the end of the process, a larger concentration of substances is on one side of cell membrane than the other.
B no energy is used during the transport
C the end result is dynamic equilibrium of substances on both sides of the cell membrane
D moves substances with or down the concentration gradient
E uses AT{ (energy) from cell
F move substances of moving substances from LOW to HIGH concentrations
G the process of moving substances from HIGH to LOW concentrations

Answers

The statements that describe active transport are as follows:

At the end of the process, a larger concentration of substances is on one side of cell membrane than the other.uses ATP (energy) from cellmove substances from low to high concentrations

WHAT IS ACTIVE TRANSPORT?

Active transport is the process whereby molecules or substances are moved from a region of lower concentration to a region of higher concentration across a membrane.

Active transport moves molecules against a concentration gradient, hence, requires the input of energy for it to occur.

Based on the above explanation, the statements that describe active transport are as follows:

At the end of the process, a larger concentration of substances is on one side of cell membrane than the other.uses ATP (energy) from cellmove substances from low to high concentrations

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Using knowledge of intermolecular forces, explain why the yellow food coloring mixed with the water and the acetone was able to remove the blue dye from the glitter. (Basically the experiment was we mixed yellow food coloring with acetone and water and added it to glitter, and it removed the blue dye from the glitter. Please mention intermolecular forces in your answer.) the head of a nail is 0.39 cm0.39 cm in diameter. you hit it with a hammer with a force of 27 n.27 n. what is the pressure pheadphead on the head of the nail? match it in the correct order the text of country or rural blues that arose in the mississippi delta after the civil war a. voiced the difficulties of everyday life. b. typically consisted of a three-line stanza. c. was set to a repeating harmonic pattern. d. all answers are correct. A sample of helium gas occupies 12.4 L at 23C and 0.956 atm. What volume will it occupy at 40C and 0.956 atm? ___L The table of values shows a linear relationship between x and y. What is the slope of the line represented by the table of values?A. -8/5B. -5/8C. 8/5D. 5/8 4the everglades' climate is _____________ than in most other parts of the united states. What is the most abundant element on Earth?A oxygenB CobaltC CarbonD Iron5Any substance represented by a chemical formulaA Homogenous mixtureB Heterogenous MixtureC elementsD pure substance what is the slope of the line?? help! Is Snowball still alive in Animal Farm? One of the main financial services that is provided by a bank involves offering accounts where people can safely store their money for a period of time, all the while earning interest and being protected by insurance. What is this common financial service called?. Which of the following is a substance that can pass through the walls of lymphatic capillaries, but normally cannot pass through the walls of blood capillaries? Multiple Choice Proteins Water Glucose 28. Which of the following phrases from the passage contains a pluralpossessive noun?a. flowers and pineconesb. her friends, her sister, or her sister's friends.C. put on make-believe playsd. The kids' plays Nina attends many seminars. she wants to improve her listening skills. What advice will you give her? A. Look at the responses of other people in the audience. B. Listen to the beginning and end of the talks attentively. C. Read up on the speaker to get an idea of his or her views. D. Pay attention to the speakers tone of voice. explain the different methods that can be used to model the motion of an object. Plz help I dont understand HELP!! NOT MUCH TIME LEFT!!!WILL MARK BRAINLIEST Which career pathways are a part of the Manufacturing career cluster? Select all that apply.Manufacturing Production Process DevelopmentProductionMaintenance, Installation, and RepairLegal ServicesLogistics and Inventory ControlQuality AssuranceBusiness Financial ManagementHealth, Safety, and Environmental Assurance PLZ PLZ HELP ME ILL MARK BRAINLIEST AND GET A FOLLOW BUT PLZ HELP ME What is x, The width of the triangle in centimetersA 78cmB 13cmC 5.6D 144cm Select all that are true regarding changes in markets changes in quantity are from a change in the willingness to pay or willingness to accept changes in supply or changes in demand result in a shift of the functions (lines) on the market graph changes in supply or changes in demand refer to changes in the function (relationship between price and quantity) changes in supply or changes in demand are from the same willingness to pay or willingness to accept changes in quantity result from movement along an existing demand or supply function changes in quantity refer to movement along an existing supply or demand curves