mutation in the fibroblast growth factor receptor (fgfr) gene results in achondroplasia (dwarfism), which is a dominant condition caused by a single base substitution (ggg>agg) that changes the amino acid glycine at position 480 to arginine (g480r) in the fgfr protein. normally, fgfr is active when fgf binds to it and inhibits excessive bone growth, but the mutant fgfr is constantly active even when fgf is not bound to it. how can gene therapy be attempted to treat achondroplasia?

Answers

Answer 1

The gene therapy can be attempted to treat achondroplasia is by RNAi that knocks down the mutant FGFR expression, Adeno-associated viral (AAV) vector that carries the wild-type FGFR and CRISPR with the wild-type FGFR donor DNA.

Gene therapy is a cutting-edge method for treating or preventing genetic illnesses. Correction of the specific DNA sequence would repair the protein, curing the disease since mutant DNA in genetic diseases codes for mutant proteins.

Gene therapy can make advantage of RNA interference. By blocking the production of the proteins that the genes code for, it is a method for "silencing" genes. It is a form of gene therapy that utilizes the transition between DNA and protein.

AAV-mediated gene targeting refers to the homologous recombination process through which AAV vectors can integrate. Thus, this vector that carries the wild-type FGFR can be incorporated into the achondroplasia patient.

Using the gene-editing tool CRISPR/Cas9, it is possible to add, remove, or modify a specific section of a gene's DNA sequence. Thus, the damaged section of the mutant FGFR's DNA can be removed using this technique.

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Related Questions

developing nations such as India and somalia are likely to have what type of age structure graph?​

Answers

Answer:

These nation you've stated ofcourse are still a developing nation, therefore its population are majority young in around 6-18 due to lack of literacy and alot of people are in poverty

Explanation:

If the Peclet number for the transport of a drug in tissue is 0. 1, what is the dominant mechanism of transport?

Answers

The Peclet number for the transport of a drug in tissue is 0. 1, the dominant mechanism of transport is Diffusive transport.

Diffusive transport is a far more sophisticated mechanism than convective transport in porous electrodes. The electrochemical reactions that occur within the catalyst layer's three border zones consume the reactants to produce the end products. This results in component concentration gradients inside the catalyst layer and throughout the gas diffusion layer. The concentration gradients are the primary drivers of species diffusive movement.

The Péclet number is a class of dimensionless numbers that may be used to explore transport processes in a continuum. It is defined as the ratio of a physical quantity's rate of advection by flow to the rate of diffusion of the same quantity driven by an appropriate gradient.

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cancer is a disease in which cells exhibit uncontrolled cell division. drugs used in the study of microtubules are also used in the treatment of cancer. why are drugs that disrupt microtubules more useful in the treatment of cancer than are drugs used to disrupt microfilaments? what is the name of the category of these drugs that describes their function?

Answers

Drugs that disrupt microtubules are more useful in the treatment of cancer than drugs that disrupt microfilaments because microtubules are critical components of the cell's cytoskeleton and are involved in many essential cellular processes, including cell division.

By targeting microtubules, these drugs can disrupt the normal cell cycle and prevent cancer cells from dividing and proliferating. Microtubule-targeting drugs can also induce cell death by disrupting the microtubule network, causing the cancer cell to lose its structural integrity. The category of drugs that disrupt microtubules is called microtubule inhibitors or antimitotic agents. Examples of microtubule inhibitors include paclitaxel, vinblastine, and colchicine. These drugs work by different mechanisms, such as stabilizing or destabilizing microtubules, but they all interfere with microtubule dynamics and disrupt normal cellular processes, ultimately leading to cell death. Microtubule inhibitors are used in the treatment of a variety of cancers, including breast, lung, ovarian, and prostate cancer.

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a scientist studying the inheritance of flower color found that when they crossed the offspring of two pure-breeding flower lines, one purple and one white, they observed the following f2 generation from planting 50 seeds: 12 plants with purple flowers 26 plants with lavender flowers 12 plants with white flowers what might explain these results?

Answers

12 plants have purple flowers and 12 plants have white flowers, which correspond to the purebred parents. 26 plants have a color between purple and white. These plants have a lavender color and correspond to the heterozygous parent.

The scientist studying the inheritance of flower color found that when they crossed the offspring of two pure-breeding flower lines, one purple and one white, they observed the following F2 generation from planting 50 seeds:12 plants with purple flowers, 26 plants with lavender flowers, 12 plants with white flowers. Mendel's law of segregation could explain these results.Mendel's law of segregation states that alleles of a gene pair separate during gamete formation, and each gamete receives only one of the two alleles.

This means that, during gamete formation, the alleles of a gene segregate or separate so that each gamete gets only one allele.Therefore, when the pure-breeding lines were crossed, the first generation, F1, would have all had the genotype of one dominant allele and one recessive allele. The F1 generation produced would then have had a mix of dominant and recessive alleles. Since the flower color in this case is determined by a single gene, with a dominant and recessive allele, and neither the purple nor the white allele is completely dominant over the other, this explains the observed flower colors in the F2 generation.

Therefore, 12 plants have purple flowers and 12 plants have white flowers, which correspond to the purebred parents. 26 plants have a color between purple and white. These plants have a lavender color and correspond to the heterozygous parent.

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CAN ANYONE PLSSS HELP WITH THESE QUESTIONS

CAN ANYONE PLSSS HELP WITH THESE QUESTIONS

Answers

1- photosynthesis
2- glucose


Your welcome!

Answer:

The first one is B

Explanation:

true or false: low calorie diets increase the free radical activity in cells, thus increasing the life span of the cell.

Answers

False. Low-calorie diets do not increase free radical activity in cells. In fact, research has shown that reducing calorie intake, particularly through a method known as caloric restriction.



Caloric restriction involves reducing daily calorie intake without causing malnutrition. This approach has been shown to extend the life span of various organisms, including yeast, worms, flies, and rodents. One of the mechanisms behind this is thought to be the reduction of free radical production and oxidative damage within cells.


Free radicals are unstable molecules that can cause damage to cellular components such as DNA, proteins, and lipids, leading to aging and disease. Reducing calorie intake can lower the metabolic rate and oxidative stress, thereby decreasing the production of free radicals.In summary, low-calorie diets do not increase free radical activity in cells. Instead, they may help reduce free radical production and oxidative stress, potentially increasing the life span of cells.

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A genetic mutation causes a squirrel to be born with much darker fur than its parents.

How will this mutation most likely affect the squirrel population?

Because the trait was caused by a mutation, it will not be passed on to any offspring, resulting in the disappearance of the trait.
Because the trait was caused by a mutation, it will be passed on to offspring over many generations, resulting in a population of darker squirrels.
If the trait is unfavorable, it will be passed on to offspring over many generations, resulting in a population of darker squirrels.
If the trait is favorable, it will be passed on to offspring over many generations, resulting in a population of darker squirrels.

Answers

Answer: If the trait is favorable, it will be passed on to offspring over many generations, resulting in a population of darker squirrels.

The mutation most likely affects the squirrel population if the trait is favorable, it will be passed on to offspring over many generations, resulting in a population of darker squirrels. The correct option is D.

What is mutation?

A mutation is a change or modification in the DNA or gene sequence of the organism. The modification is done due to mutagens. These mutagens delete or insert or replace the bases and cause differences.

Here, due to mutation, the color of the squirrel changed to black, so if the gene of black color will be transferred to future generations, it can be dominant or recessive.

Thus, the correct option is D, If the trait is favorable, it will be passed on to offspring over many generations, resulting in a population of darker squirrels.

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four of the five answers listed below assist in chromosome movement. select the exception

Answers

The exception of the four answers listed below that assist in chromosome movement is the Nuclear envelope. The correct answer is (E).

The nuclear envelope is not directly involved in the process of chromosome movement. Chromosomes contain genetic material in the form of DNA molecules. The correct option is e) Nuclear envelope.

Chromosomes are made up of proteins and DNA and carry genetic information in the form of genes. Chromosomes play an important role in cell division by ensuring that genetic information is properly separated between daughter cells. They attach to spindle fibers during cell division, ensuring that each new cell receives the correct number of chromosomes.

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Q- Four of the five answers listed below to assist in chromosome movement. Select the exception.

a. Kinetochores

b. Centromeres

c. Centriole

d. Spindle microtubule

e. Nuclear envelope

how many inches thick should the bear's fur layer ( lfur ) be to hold a layer of air lair so that adequate insulation is provided?

Answers

Answer: 45 inches long

Explanation:

Please help!

infer why scientists hypothisize that chemical events preceded the orgin of life on earth

Answers

Answer:

It is exclusively a philosophically naturalistic perspective of universal reality that is allowed in any hypothesis of the origin of life, meaning only the interactions of elements that through naturalistic processes that are allowed for any postulation of what could precede the appearance of life. However, chemical evolution that attempts to explain the interaction of abiotic materials, elements, compounds, molecules and assemblies are mythological, just as is Darwin's "warm little ponds" and increasingly, the primordial soup of Oparin-Haldane. There are no naturalistic processes capable of any significant organization and assembly of biochemical compounds. The physics law of entropy does permit assembly of some materials, even simple amino acids and sugars, but nothing even close to what is required in an organism, even of the simplest construction. The lab experiments that have been performed and have demonstrated some biochemical assembly have been intelligent design, highly managed efforts that are not geochemically relevant to primordial earth conditions.

what the person above me said is correct


What charge do protons have in an atom?

Answers

Answer and Explanation:

+1

The other two particles are the neutron and electron. Protons are found in the nucleus of the atom. This is a tiny, dense region at the center of the atom. Protons have a positive electrical charge of one (+1) and a mass of 1 atomic mass unit (amu), which is about 1.67×10−27 kilograms.

How are the chromosomes in the eukaryotic cells different from those in prokaryotic cells

Answers

Answer: Eukaryotic chromosomes are in the nucleus and prokaryotic chromosomes are in the nucleoid.

Explanation: The main difference is that eukaryotic cells have a membrane-bound nucleus and prokaryotic cells don't have a nucleus.

The lac operon in E.coli regulates genes that code for enzymes required for the breakdown of lactose. The lac operon is
operon that is activated in the presence of

Answers

The lac operon in E.coli regulates genes that code for enzymes required for the breakdown of lactose. The lac operon is an inducible operon that is activated in the presence of lactose.

It is a cluster of genes in bacteria that is responsible for the metabolism of lactose. The lactose operon consists of three structural genes, lac Z, lac Y, and lac A, that code for enzymes that break down lactose, and a regulatory region, which includes the promoter, operator, and lac I gene. It functions as a switch that turns genes on or off in response to environmental changes. The regulatory region of the lactose operon contains the operator and the promoter. The operator is a DNA sequence that regulates the expression of the genes by acting as a binding site for the regulatory protein.

The promoter is a DNA sequence that is recognized by RNA polymerase, which initiates the transcription of the genes. The lac I gene codes for a regulatory protein called the lac repressor. The lac repressor binds to the operator region of the lac operon and prevents RNA polymerase from transcribing the genes. In the absence of lactose, the lac repressor is active and the lac operon is turned off.

When lactose is present in the environment, it binds to the lac repressor and changes its conformation, preventing it from binding to the operator. This allows RNA polymerase to bind to the promoter and transcribe the genes necessary for lactose metabolism. Thus, the lactose operon is an inducible operon that is activated in the presence of lactose.

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_______________ survivorship curves are usually associated with organisms that have high mortality rates in the early stages of life.

Answers

Type III survivor-ship curves are usually associated with organisms that have high mortality rates in the early stages of life. It is initially very steep which is reflective of very high morality among young but flattens out those individuals who reach maturity survive for longer time.

The number of individuals in population that can be expected to survive to any specific age. A type III survivorship curves depicts species where few individuals will live to adulthood and die as they get older because the greatest morality only for those individuals is experienced in life,

This type of survivorship curve is drawn as a concave curve on a graph. Tree and marine invertebrates exhibits a type III curve. Type I survivorship curve is most common and has flat curve reflects low juvenile mortality with individual living to old age.

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Help me please!!!!! :((

Help me please!!!!! :((

Answers

i’m pretty sure the answer is A

Answer:

the answer seems to be A

Vocabulary. Match the definitions to the words they describe

Vocabulary. Match the definitions to the words they describe

Answers

DEABFC in order, that’s the answer

1
In which of the following ways does the respiratory system help to maintain homeostasis
during exercise?

Answers

Answer:

The respiratory system maintains homeostasis during exercise by increasing breathing rate to match the consumption of oxygen to make ATP. Your lungs also increase in size during exercise. This happens so that your body can take in more oxygen and get rid of the extra carbon dioxide that has built up in the blood. These processes work together in many ways for the respiratory and circulatory systems achieve homeostasis during exercise

Explanation:

+
B
!!
= = = =
3. If the characteristic is absent in the animal, place a "." in the correct column, indicating that the animal
does not have that particular characteristic.
Table of Derived Characters:
Characteristic
Organism
Jaws
Limbs
Hair
Lungs
Opposable
thumb
Upright,
erect
posture
+
+
Lamprey
Trout
Caecilian
Turtle
Cat
Gorilla
Human
Total

+B!!= = = =3. If the characteristic is absent in the animal, place a "." in the correct column, indicating

Answers

Answer:

human is all the would becouse humanity important

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Ummmmm what happening

13-15.) In proton-beam therapy, a high-energy beam of protons is fired at a tumor. As the protons stop in the tumor, their kinetic energy breaks apart the tumor's DNA, thus killing the tumor cells. Fo

Answers

Proton-beam therapy is a type of radiation therapy used to treat cancer. In this therapy, a high-energy beam of protons is directed at a tumor. The protons have a specific range in tissue, and they stop inside the tumor, delivering most of their energy at the tumor site.

The main advantage of proton-beam therapy over traditional radiation therapy is that it can deliver a high dose of radiation to the tumor while minimizing damage to the surrounding healthy tissues. This is because protons have a unique physical property called the Bragg peak, which allows them to deposit their maximum energy at a specific depth within the tissue.

When the high-energy protons stop in the tumor, their kinetic energy is transferred to the tumor cells. This energy breaks apart the tumor's DNA, which is responsible for the cells' ability to grow and divide. By damaging the DNA, the tumor cells are unable to replicate and eventually die.

It is important to note that proton-beam therapy is a complex and specialized treatment that requires careful planning and precise delivery. It is typically used for tumors located near critical structures, such as the brain or spinal cord, where minimizing damage to surrounding tissues is crucial.

In summary, proton-beam therapy uses high-energy protons to deliver radiation to tumors, damaging their DNA and killing the tumor cells. This treatment offers the advantage of delivering a focused dose of radiation while minimizing harm to healthy tissues.

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Please help me with this problem

Please help me with this problem

Answers

Answer:

A

Explanation:

Explain why some mutations are more harmful than others

Answers

Some mutations are more harmful than others because some mutations can lead to death , while others are actually good for you - can help benefit your body

The ultimate goal of the male reproductive system is to:
a. ensure that sperm is produced at the correct time, coinciding with ovulation.
b. release sperm into the female's reproductive system.
c. join sperm with an egg in an environment that favors fertilization.
d. produce large numbers of sperm.
e. maintain the homeostatic condition of the male's body.

Answers

The ultimate goal of the male reproductive system is to join sperm with an egg in an environment that favors fertilization. The correct option is C.

This goal is achieved through a series of coordinated processes and structures within the male reproductive system. The primary function of the male reproductive system is to produce, store, and deliver sperm cells.

Sperm production occurs in the testes through the process of spermatogenesis. Once produced, the sperm cells are stored and matured in the epididymis.

During sexual arousal, the sperm cells are propelled through the vas deferens, seminal vesicles, prostate gland, and urethra to be released into the female's reproductive system during ejaculation.

The ultimate objective is for the sperm to reach the female reproductive tract and successfully fertilize an egg, leading to the initiation of pregnancy. The correct option is C.

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Which of the following best describes the genetic complement in each
daughter cell at the conclusion of meiosis?
A. A haploid set of chromosomes that are a recombination of the
parents' chromosomes
B. A diploid set of chromosomes that are identical to the parents'
chromosomes
C. A diploid set of chromosomes identical to the other daughter cells'
chromosomes
D. A haploid set of chromosomes that are identical to the parents'
chromosomes

Which of the following best describes the genetic complement in eachdaughter cell at the conclusion of

Answers

Answer:

A

Explanation:

Meiosis end in four daughter cells that are haploid and contain half the chromosomes as the parent cell and genetically different from the parent cell and from each other, so A would be the right answer.

Which of the following best describes the genetic complement in eachdaughter cell at the conclusion of

A haploid set of chromosomes that are a recombination of the parents' chromosomes  best describes the genetic complement in each daughter cell at the conclusion of meiosis.

What do you mean by meiosis?

Meiosis is a special type of cell division of germ cells in sexually-reproducing organisms that produces the gametes, such as sperm or egg cells.

Moreover, meiosis is a type of cell division that reduces the number of chromosomes in the parent cell by half and produces four gamete cells.

Meiosis is important for three main reasons: it allows sexual reproduction of diploid organisms, it enables genetic diversity, and it aids the repair of genetic defects.

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as they walked through the haunted house, every room heightened their fear and anxiety. the walls of one room moved to close in around them, while in another they had to lie in coffins, which then opened up beneath them. which division of their ans was most active, and which neurotransmitter(s) would be involved in this pathway? select all that apply.

Answers

The sympathetic nervous system (SNS) is likely most active during the haunted house experience. The SNS is the part of the autonomic nervous system that activates the body's "fight-or-flight" response.

This response causes a release of the neurotransmitters adrenaline and noradrenaline, resulting in increased heart rate, sweating, and other physiological changes.

In addition, other neurotransmitters such as dopamine and serotonin may also be involved. Dopamine is typically involved in feelings of pleasure, but when released too quickly or in large quantities it can cause feelings of fear. Serotonin is linked to feelings of well-being, but it can also be involved in feelings of anxiety.

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As they walked through the haunted house, every room heightened their fear and anxiety. the walls of one room moved to close in around them, while in another they had to lie in coffins, which then opened up beneath them. which division of their answer was most active, and which neurotransmitter(s) would be involved in this pathway? select all that apply.

A. sympathetic nervous system

B. Central nervous system

C. Peripheral nervous system

D. none

PLEASE ANSWER QUICK
The figure presents a diagram of adding d T M P to a growing strand of D N A. A D N A template that consists of nine nucleotides is shown. Five nucleotides have already been added to the complementary strand that is growing from left to right along the template. The left end of the growing strand is labeled 5 prime, and the right end is labeled 3 prime. The left end of the template strand is labeled 3 prime, and the right end is labeled 5 prime. An incoming d T T P has three phosphate groups. Arrows indicate that the two outermost phosphate groups split off as the d T M P with the remaining phosphate group is about to join to the 3 prime end of the growing strand.
Figure 1. Model showing details of adding a deoxythymidine monophosphate (dTMP) nucleotide to a growing strand of DNA

The features of this model provide evidence for which explanation of why all growing strands are synthesized in a 5′ to 3′ direction?


A. The two strands need to be antiparallel to bond properly.


B. Thymine and adenine would not bond properly if the strand grew from 3′ to 5′.



C. The translation of mRNA occurs in the 5′ to 3′ direction; therefore, the growing DNA strand must also grow in the 5′ to 3′ direction.


D. The phosphate group, attached to the 5′ carbon of the dTMP, forms a covalent bond with the oxygen atom attached to the 3′ carbon of the growing strand.

Answers

Answer:

D - The phosphate group, attached to the 5′ carbon of the dTMP, forms a covalent bond with the oxygen atom attached to the 3′ carbon of the growing strand.

Explanation:

I got it checked and it was right

The feature of the model provides evidence in a 5′ to 3′ direction is the phosphate group, attached to the 5′ carbon of the dTMP, forms a covalent bond with the oxygen atom attached to the 3′ carbon of the growing strand. The correct option is D.

What are DNA bases?

The sequence of DNA bases is referred to as the DNA sequence. RNA and DNA are both genetic elements composed of nucleic acids composed of deoxyribose acid, while RNA is composed of ribonucleic acid.

Both DNA and RNA have four bases that are linked together by a hydrogen bond. RNA has uracil in place of thymine, but DNA has timing and all other bases are the same.

Therefore, the correct option is D. The phosphate group, connected to the dTMP's 5′ carbon, creates a covalent bond with the oxygen atom associated with the developing strand's 3′ carbon.

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Species more likely to become endangered require A. pristine habitats
B. late successional ecosystems. C. A and B only D. A, B and C E. ecosystems found on the right hand side of the logistic curve describing ecological development over time.

Answers

Species more likely to become endangered require pristine habitats and late successional ecosystems. The correct option is C. A and B only.

An endangered species is a species that is at risk of extinction or is declining rapidly in population. Endangered species are those that have been classified by the International Union for Conservation of Nature (IUCN) as at risk of extinction in the wild.

A pristine habitat is a habitat that has never been impacted or damaged by human activity. These habitats are free of human-caused disturbances, such as habitat destruction, pollution, or invasive species.

Late-successional ecosystems are those that have reached a climax or stable state. These ecosystems are the most mature and diverse, with a wide range of species. The ecosystems that have been undisturbed for a long period of time are those that are late-successional ecosystems. Species that are more likely to become endangered require pristine habitats and late-successional ecosystems. These types of ecosystems are rare and fragile and are easily impacted by human activities. Therefore, conservation measures must be taken to ensure that these ecosystems are protected from human disturbance and other forms of damage.

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9. Addinn Fvira ne: Unltame Sautra facun 3. Changing The Direction of Diode QUFSTIONS: 1. Why are these versions of diode circuits called clamping circuits? What is the meaning of clamp? 2. What could

Answers

Clamping circuits are versions of diode circuits that are used to clamp the signal waveform to a fixed dc level. Clamping circuits can be used for a variety of purposes, such as level shifting, waveform generation, and circuit protection.

1. These versions of diode circuits are called clamping circuits because they clamp the signal waveform to a fixed dc level. Clamp means to firmly grip or fasten something or to prevent something from moving or changing. A clamping circuit in electronics does exactly that. It clamps the input signal at a fixed level to produce an output signal.

2. Clamping circuits can be used for a variety of purposes, such as level shifting, waveform generation, and circuit protection. They are used to protect electronic circuits from voltage spikes or transients and to stabilize power supply voltage levels. They are also used in audio and video applications to remove unwanted DC offset from the input signal and to generate a reference voltage for the amplifier.

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Why does mitosis/asexual reproduction occur in all organisms?

Answers

Answer: Asexual reproduction is the duplication of the genetic material from a parent organism to create a new organism. in mitosis also the cell first makes the division of cytoplasm takes place and thus the parent cell divided itself into 2 daughter cells which are like each other.

(You can find all this on google)

Hope this helps!

Explanation:

Clouds form when air is ? A) swirled by wind. B) heated by the sun. turned into ozone. D) transpired by plants.​

Answers

Answer: transpired

Explanation:  PLEASE GIVE BRAINLIEST IT HELPS ALOT

Answer: heated by the sun

Explanation:

When the Sun warms the Earth, warm air rises into the atmosphere. As it rises, it expands and cools. Water vapor condenses out of the cool air to form a cloud.

Other Questions
Find the average value of f(x)=5x4+4x10over the interval [2 , 2]-1043356726-67-151151-335104-26 metropolitan edison company owned and operated two nuclear-fueled power plants at three mile island near harrisburg, pennsylvania. both power plants were licensed by the nrc after extensive proceedings and investigations, including the preparation of the required environmental impact statements. when one of the power plants was shut down for refueling, the other plant suffered a serious accident that damaged the reactor. the governor of pennsylvania recommended an evacuation of all pregnant women and small children, and many area residents did not leave their homes for several days. as it turned out, no dangerous radiation was released. people against nuclear energy (pane), an association of area residents who opposed further operation of the nuclear power plants at three mile island, sued to enjoin the plants from reopening. they argued that the reopening of the plants would cause severe psychological health damage to persons living in the vicinity and serious damage to the stability and cohesiveness of the community. are these reasons sufficient to prevent the reopening of the nuclear power plants? is it socially responsible for the federal government to permit the operation of nuclear power plants? metropolitan edison company v. people against nuclear energy, 460 u.s. 766, 103 s.ct. 1556, 1983 u.s. lexis 21 (supreme court of the united states) A colon is best used to connect two independent clauses whenSelect one:1.the second clause is an elaboration of the first clause. 2.the first clause is the cause and the second clause is the effect.3.the first clause contains a list. 4.the second clause contains a quotation. Please help I reallllly need the help The current population of a small town is 5914 people. It is believed that town's population is tripling every 11 years. Approximate the population of the town 2 years from now. residents (round to nearest whole number) Write your answer as a fraction or as a whole or mixed number2 6/8 + 3 5/8 = What two reasons did Mary Wollstonecraft present for giving women equal rights? What are the dimensions of the rectangle shown on the coordinate plane?On a coordinate plane, a rectangle has points (2, 2), (2, 5), (negative 5, 2), (negative 5, 5).A. The base is 5 units and the height is 3 units.B. The base is 4 units and the height is 7 units.C. The base is 7 units and the height is 5 units.D. The base is 7 units and the height is 3 units. Use MATLAB to compute the smallest eigenvalue of the 100 x 100Pascal matrix. PLEASE HELP FIRST CORRECT ANSWER GETS BRAINLIEST AND LOTS OF POINTS JUST FOR ANSWERING Read the excerpt from "Rebuilding the CherokeeNation."One of the things that I saw, just as if you look at whathappened after the Trail of Tears, you can look at someof the positive things that happened among our people.What I looked at in our communities is I saw among ourpeople they had unbelievable tenacity. Our tribe isone of the most acculturated tribes in the country, andyet there are thousands of people who still speakCherokee. Ceremonies that we've had since thebeginning of time are still going on in a tribe asacculturated as ours is. Our people are very tenacious,and it was that tenacity that I saw as a strength wecould build on.Courtesy of the Wima Mankiller TrustMark this and returnWhich sentence best integrates a direct quotation fromthe excerpt?O Wilma Mankiller notes the essential quality she feelsbrought the Cherokee through the Trail of Tears:"they had unbelievable tenacity.O Wilma Mankiller boasts about the Cherokeepeople's abilities with language: "there arethousands of people who still speak Cherokee."O Wilma Mankiller feels that Cherokee people, despitebeing acculturated, "have a strength they can buildon."Wilma Mankiller credits her tribe's survival toperforming "ceremonies that we've had since thebeginning of time." Communication as the means of coming to know who we are is known as satisfying ________ needs. If you only use part of a quotation, it is not necessary to include a citation. Parallelogram HIJK with vertices H(-1,3),I(-1,-1),J(2,-2),and K(2,2) over the y-axis. The postInvalidate method of the View class that has no parameter triggers a call to the __________________ method and refreshes the whole View. Debt is measured relative to GDP because: when ethylbenzene reacts with bromine in a free radical halogenation, a small amount of product that contains no bromine is formed. show the mechanism of how the product is formed and the product. explain why only a small amount of that product is formed. (10 pts) 2-methylprop-1-ene styrene o-xylene Beams of different frequency electromagneticradiation are listed below. Each beam has the same total energy.Rank these beams on the number of photons in each beam.green light, FM Radio wave, x-ray, yellow light, gamma ray, AMradio wave a corporation's earnings divided by the number of outstanding shares of a firm's common stock is called The treatment of iron-deficiency anemia includes _____. a. substitution of whole milk with soy milk b. a low-fat diet c. exclusion of nonmeat sources of iron d. supplementation with iron drops at a dose of 3 mg/kg per day e. excess intake of goat's milk