The mutation in the beta-globin allele into the sickle cell allele can be detected by Denaturing gradient gel electrophoresis or DGGE.
It uses electrophoresis to find single base alterations in a DNA segment. Double-stranded DNA is subjected to an increasing denaturing environment in a denaturing gradient acrylamide gel and will melt in distinct regions known as "melting domains." These domains' melting point (Tm) varies depending on the sequence.
The DNA will partially melt when the lowest melting domain's Tm is reached, resulting in branched molecules. DNA loses some of its mobility in a polyacrylamide gel when it partially melts. The presence of a mutation will change the DNA's melting profile when compared to wild type because the Tm of each melting domain is sequence-specific. DNA with mutations will experience mobility shifts at various locations in the gel compared to the wild type. If the fragment completely loses its genetic makeup, migration once more depends on size.
Hence, difference in normal and mutant DNA sequence can be observed in gel.
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If b is dominant over b, list the offspring that will exhibit or show the dominant trait.
Answer:
if its BB or Bb the offspring will show the dominant trait
Explanation:
If its bb then the trait wont be expressed
WHAT IF? In Figure 18.17b , the lower cell is synthesizing signaling molecules, whereas the upper cell is expressing receptors for these molecules. In terms of gene regulation and cytoplasmic determinants, explain how these cells came to synthesize different molecules.
The cells came to synthesize different molecules through differential gene regulation and the presence of specific cytoplasmic determinants.
Differential gene regulation plays a crucial role in determining the synthesis of different molecules in cells. Each cell possesses the same genetic information in the form of DNA, but different genes are activated or repressed in specific cells, leading to the production of distinct molecules. This regulation is achieved through the binding of transcription factors and other regulatory proteins to specific regions of the DNA, influencing gene expression.
In the given scenario, the lower cell synthesizes signaling molecules because the genes responsible for their production are activated in that cell. These genes may contain specific regulatory elements or transcription factor binding sites that are absent or inactive in the upper cell. As a result, the transcription of these genes is initiated, leading to the synthesis of signaling molecules.
On the other hand, the upper cell expresses receptors for these signaling molecules. It is likely that the genes encoding these receptors are activated in the upper cell due to the presence of different regulatory elements or the binding of specific transcription factors. This activation allows the cell to produce the necessary receptor proteins to detect and respond to the signaling molecules produced by the lower cell.
Cytoplasmic determinants, which are specific molecules or factors present in the cytoplasm of the cells, can also contribute to the differential synthesis of molecules. These determinants can be localized during cell division or inherited from the parent cell, leading to distinct patterns of gene expression and protein synthesis in daughter cells.
In summary, differential gene regulation and the presence of specific cytoplasmic determinants result in the synthesis of different molecules in the lower and upper cells. These mechanisms allow for cellular specialization and the establishment of communication pathways between neighboring cells.
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Rainforests around the world are being cleared at an alarming rate to make room for new communities, agriculture, mining, and roads, and to provide lumber for construction and furniture.
How might the destruction of rainforests affect the balance of gases in Earth's atmosphere?
A by increasing carbon dioxide and decreasing oxygen
B by increasing carbon dioxide and increasing oxygen
C by decreasing carbon dioxide and increasing oxygen
D by decreasing carbon dioxideand decreasing oxygen
What Macromolecules does the skeletal system require to function properly?
Answer:
The major components of bone tissue at the molecular scale are minerals, water, collagen, and other proteins. At the next level of organization, small crystals of hydroxyapatite made of calcium and phosphate are embedded within collagen fibers to produce a composite (blended) material with high compressive and tensile strength.
The skeletal system protects and supports vital organs, allows our body to move, stores important minerals, and produces blood cells. There are several chemical elements and molecules required to maintain the many functions of the skeletal system. The chemical properties of these components support bone structure and function. On a chemical level, bone is divided into inorganic and organic (carbon-containing) components.
The primary inorganic components of bone are:
calcium, which is required for many functions throughout the body;
phosphorus (in the form of phosphate ions), which is a component of buffer systems and energy-rich molecules; and
water, which contributes to the compressive resistance of bone and contributes to the fluid matrix of bone.
The primary organic components of bone are:
collagen, the major structural protein (type I in bone and type II in cartilage); and
proteoglycans, which are negatively charged glycosylated proteins (glycosylated means having carbohydrate sugar groups modifying the protein).
Bone is approximately 60 to 70 percent inorganic mineral and 10 percent water by weight. The remaining 20 to 30 percent of bone is organic matrix (osteoid), such as collagen and proteoglycans. Your body contains 1 to 2 kilograms of calcium and nearly 600 grams of phosphorous. Nearly 99 percent of the calcium and 86 percent of the phosphorous is stored in your bones.
Inorganic Components of Bone
Calcium ions (Ca2+) are stored in bone tissue, but can be released into the bloodstream when blood levels fall below optimal. Blood calcium is important for muscle contractions, nerve impulses, and blood clotting.
In bone, phosphorous (P) is found in the form of phosphate ions (H2PO4–). Outside of bone, phosphorous plays roles in energy storage (such as in ATP), and is required for the formation of DNA and RNA. Therefore, it is required for cellular growth, maintenance, and tissue repair.
When combined with hydrogen, phosphorous forms dihydrogen phosphate ions (H2PO4–). Dihydrogen phosphate acts as a buffer to maintain a constant pH balance by acting as either a hydrogen ion donor (acid) or a hydrogen ion acceptor (base). In all cells, a constant pH must be maintained to carry out cell functions.
Explanation:
Study the map. Which plate forms a boundary with the African Plate?
Answer:
down below
Explanation:
The western edge of the African Plate is a divergent boundary with the North American Plate to the north and the South American Plate to the south which forms the central and southern part of the Mid-Atlantic Ridge.
Answer:
south american
Explanation:
which of the following is always true concerning the base composition of dna? a. in a molecule of double stranded dna, the ratio of adenine residues to thymine residues equals the ratio of cytosine residues to guanine residues. b. in a molecule of double stranded dna, the number of adenine residues plus thymine residues equals the number of cytosine residues plus guanine residues c. in each single strand, the number of adenine residues equals the number of thymine residues d. in each single strand, the number of purine residues equals the number of pyrimidine residues e. in each single strand, the number of adenine residues equals the number of guanine residues
This is due to the fact that in a dsDNA, guanine pairs with cytosine and adenine pairs with thymine. But the mole ratio of purines in the DNA of the sample that was provided.
Is it accurate to say that the base pairs adenine and guanine make up a DNA molecule?two DNA bases. Adenine (A) and thymine (T) and cytosine (C) and guanine (G) pair together in typical circumstances for nitrogen-containing bases. Adenine and thymine are always equal, but are they always paired .
Together to form the structure of DNA?Imagine a DNA strand. Adenine and thymine are always equal, as are cytosine and guanine, therefore we may calculate the percentages of each base by pairing it with a certain partner.
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_______use sunlight to store energy________and release energy to the cell.
chloroplast/mitorondria
or
mitorondria/chloroplast
Answer:
Mitorondria/chloroplast
Explanation:
I am just guessing
In a DNA molecule, the number of adenine bases equals the number
of thymine bases because thymine on one strand bonds to adenine
on the other strand.
True or false
It is TRUE that in a DNA molecule, the number of adenine bases equals the number of thymine bases because thymine on one strand bonds to adenine on the other strand.
DNA COMPOSITION:
DNA is composed of nucleotides subunits. There are four nucleotides present in the DNA molecule namely: Adenine, Cytosine, Guanine and Thymine. Adenine and Thymine hydrogen bond together while Cytosine and Guanine hydrogen bond together i.e. A-T, G-C. According to Chargaff rule, the amount of adenine bases equals the amount of thymine bases while the amount of guanine bases equals the amount of cytosine bases. This is because adenine on one strand of DNA bonds to thymine on the other strand of DNA, hence, they must be in the same amount.Learn more: https://brainly.com/question/12683542?referrer=searchResults
Pls help its past due
An index fossil must meet three criteria: it must be easily identifiable, have a wide geographical distribution, and be found in a narrow range of strata (i.e. a specific time period).
What is geographical?Geographical refers to the study of the physical features of the Earth and its atmosphere, including the location, distribution, and relationships between different natural and man-made features. It is concerned with the surface of the Earth, its landforms and climates, its physical features and its oceans and rivers, as well as the people who inhabit it.
By looking at the characteristics of the fossil, its age and its location, scientists can determine whether or not it is an index fossil. For example, if the fossil is easily identifiable, has a wide geographical distribution, and is found in a narrow range of strata, it is likely an index fossil. Additionally, scientists can look at the fossil’s age and compare it to other known fossils to see if it is an index fossil. If the fossil is found in a wide variety of strata and its age is within a certain range, it is likely an index fossil.
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The movement of waves in the middle of the ocean is normally
static
vertical
circular
horizontal
Answer:
Vertical
Explanation:
Since we are talking about movement, and the ocean can't be static due to many things happening around and inside it can't be static.
It is not circular and not horizontal. It is vertical. The movement of waves is vertical and this is because waves don't move up and down but vertically since wind is the usual maker of waves in the middle of the ocean.
What is the weather like in Tropical rainforests?
Answer:
A tropical rainforest climate is typically hot, very humid, and wet.
Explanation:
DNA is needed to create mRNA.
True
False
Answer:
False
Explanation:
Because i am mart
Glycolysis is the first step in cellular respiration. Which option best summarizes the process?
Answer: anaerobic; 6-carbon glucose forms two 3-carbon pyruvates; forms a net total of 2 ATP
For the people that can't see the picture
Which of these forces is responsible for attracting the opposite poles of two bar magnets towards each other?
Gravitational force
Electromagnetic force
Weak nuclear force
Strong nuclear force
Answer:
The correct answer is Electromagnetic.
Explanation:
Gravitation force is what holds the planets on their axis. Weak and Strong Nuclear force have to do with Nuclear energy of some kind. Making electromagnetic the correct answer.
Waht is Environment Secretary
Answer:
Thiru Shambhu Kallolikar IAS., Principal Secretary to Government, Environment and Forests Department, Government of Tamil Nadu
Answer:
Thiru Shambhu Kallolikar IAS., Principal Secretary to Government, Environment and Forests Department, Government of Tamil Nadu
Which part of the neuron below is indicated by the arrow, and what is its function?
A. The axon carries information through electrical impulses away from the cell body to the axon terminals and then to other neurons, muscles, or glands.
B. The axon contains the nucleus that controls all the activities of the cell.
C. The dendrites regulate the substances that go in and out of the cell.
D. The dendrites carry the electrical impulses from the signal receivers to the cell body.
⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀
\(\red{\bigstar}\) Which part of the neuron below is indicated by the arrow, and what is its function?
⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀
\(\pink{\bigstar}\) \(\large\underline{\underline{\bold\green{Option. D}}}\)
⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀
✯ The dendrites carry the electrical impulses from the signal receivers to the cell body.
The process that drives an increase in antibody affinity for antigen is known as?
The process that drives an increase in antibody affinity for antigen is known as affinity maturation.
Affinity maturation is a critical mechanism in the immune response that enhances the binding strength between antibodies and antigens.
During an immune response, B cells produce antibodies that initially have low affinity for the antigen. However, through affinity maturation, the immune system undergoes a selection process to promote the production of B cells that produce antibodies with higher affinity for the antigen. This process occurs in the germinal centers of lymphoid tissues.
Affinity maturation is driven by somatic hypermutation, a process in which the genetic sequence of the antibody variable region undergoes random mutations. B cells with mutations that result in higher affinity antibodies have a selective advantage and are more likely to be activated, leading to their proliferation and differentiation into antibody-producing plasma cells.
Over time, repeated cycles of mutation, selection, and proliferation result in the production of antibodies with progressively higher affinity for the specific antigen. Affinity maturation is crucial for the development of an effective immune response and plays a significant role in the generation of long-lasting immunity.
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Which eukaryotic cell-cycle event = missing in binary fission?
a. DNA duplication
b. Karyokinesis
c. Cell growth
d. Cytokinesis
In binary fission, the eukaryotic cell-cycle event that is missing is cytokinesis. This is the process by which the cell physically divides into two separate daughter cells. In binary fission, the cell simply grows and divides into two equal-sized daughter cells without undergoing cytokinesis. This means that the two daughter cells are still connected by a thin strand of cytoplasm, and they do not become fully separated until cytokinesis occurs at a later stage in the cell cycle.
Write any three problems with the measurement of quantities that the SI unit system has solved.
Explanation:
1. they are convenient to use 2. it helps the international tade 3. it eases the exchange of material
Hunter syndrome is a rare genetic disorder in which large sugar molecules called glycosaminoglycans build up in body tissues. Hunter syndrome causes abnormalities in many organs, including the skeleton, heart, and respiratory system. In severe cases, this leads to death during the teenage years. Hunter syndrome is caused by a recessive gene on the X chromosome. If a woman who is normal (but had a father with the disease) marries a normal man, what are the chances of having a daughter affected by the disease
Answer:
Hunter syndrome is a very rare, inherited genetic disorder caused by a missing or malfunctioning enzyme. In Hunter syndrome, the body doesn't have enough of the enzyme iduronate 2-sulfatase.
Type your response in the box. This exercise will help you comprehend the widespread impact that trade has on an economy. Look around the room you are in, and list five different objects you see. List what the item is, where it was made, and why you think it was made there
Analyzing five different objects in the room and their places of manufacture allows us to understand the impact of trade on the economy. They will provide an explanation of each item, including its origin and the possible reasons for its manufacturing location.
Desk Lamp: Made in China - China is known for its manufacturing capabilities, with a large workforce and lower production costs, making it an attractive location for mass production of consumer goods like desk lamps.
Laptop: Made in Taiwan - Taiwan is renowned for its electronics industry and is a major player in laptop manufacturing due to its advanced technology, skilled workforce, and established supply chains.
Coffee Mug: Made in Thailand - Thailand has a strong ceramics industry and is known for its craftsmanship. The country's rich tradition in pottery and skilled artisans make it an ideal location for producing quality ceramic products like coffee mugs.
Picture Frame: Made in Italy - Italy has a long history of art and design, and it is famous for its craftsmanship in creating high-quality and aesthetically pleasing products. Italian picture frames often showcase intricate detailing and fine finishes.
Clothing: Made in Bangladesh - Bangladesh is a leading global textile and garment manufacturer. Its abundant labor force and lower production costs attract international brands seeking to produce clothing at a competitive price.
Each item's manufacturing location is influenced by factors such as labor costs, expertise in a particular industry, availability of raw materials, infrastructure, and government policies. Global trade allows countries to specialize in certain industries based on these factors, leading to the production of goods in different regions and their subsequent distribution worldwide.
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describe the chain of events that connects the release of cfcs from discarded refrigerators to increases in uv radiation at earth's surface.
The release of chlorofluorocarbons (CFCs) from discarded refrigerators leads to the depletion of the ozone layer, which in turn increases the amount of ultraviolet (UV) radiation reaching the Earth's surface.
When CFCs are released into the atmosphere from discarded refrigerators or other sources, they can eventually reach the stratosphere, which is the layer of the atmosphere that contains the ozone layer. Once in the stratosphere, CFCs are broken down by the energy from UV radiation, releasing chlorine atoms. These chlorine atoms are highly reactive and can catalytically destroy ozone molecules. A single chlorine atom can potentially destroy thousands of ozone molecules before it is ultimately removed from the atmosphere. Increased UV radiation at the Earth's surface can have harmful effects on living organisms. It can lead to increased risk of skin cancer, damage to DNA, harm to marine life, and impacts on ecosystems. The depletion of the ozone layer caused by CFCs is a significant environmental concern, and international efforts have been made to reduce the production and use of CFCs through agreements such as the Montreal Protocol.
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Which diagnostic tests aid in the diagnosis of cystic fibrosis?
Diagnostic tests aid in the diagnosis of cystic fibrosis is a
genetic test that looks for chromosomal abnormalities linked to cystic fibrosis (CF) is frequently performed in addition to a sweat test, which analyzes the quantity of chloride in sweat.
What is a sweat test?An example of a sweat test. The sweat test measures the amount of chloride, a component of perspiration related to salts. There are no needles used in this test. A colorless, odorless chemical (pilocarpine) and a little quantity of electrical stimulation are administered in the first step of the test to activate the sweat glands in a small region of the arm or leg to produce perspiration.
There may be some warmth or tingling there. This part of the exam takes around five minutes. The perspiration is then collected on a piece of gauze, filter paper, or a plastic coil. This process takes 30 minutes. In a medical lab, the quantity of chloride in the collected perspiration is measured.
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List four different Bible phrases that show how the Bible claims to be the Word of God.
40-point mark as brainly
Answer: 1. God created the heavens and the earth. 2. He sent his son to die for our sins. 3. he preforms mericles. 4. He Arose from the grave.
Explanation:
All Scripture is breathed out by God and profitable for teaching, for reproof, for correction, and for training in righteousness, that the man of God may be competent, equipped for every good work. (2 Timothy 3:16-17)
It is the Spirit who gives life; the flesh is no help at all. The words that I have spoken to you are spirit and life. (John 6:63)
Every word of God proves true; he is a shield to those who take refuge in him. (Proverbs 30:5)
For the word of God is living and active, sharper than any two-edged sword, piercing to the division of soul and of spirit, of joints and of marrow, and discerning the thoughts and intentions of the heart. (Hebrews 4:12)
I hope this helps!
The city of Green Valley, Arizona, is trying to determine where to locate a new fire station. The fire station is expected to serve four neighborhoods.
Neighborhood X coordinate Y coordinate Number of homes
Birchwood 0.5 3.5 172
Cactus Circle 2 0.5 42
De La Urraca 3 1.5 223
Kingston 3 1 44
a The X* coordinate of the weighted center of gravity for the new fire station is _____. Enter your response to 2 decimal places.
b. The Y* coordinate of the weighted center of gravity for the new fire station is _____. Enter your response to 2 decimal places.
c. What other factors might come into play when making the final decision?
a. Zoning Considerations
b. Distance from other fire stations
c. Available space
d. All of the above.
(a) The X* coordinate of weighted center of gravity for new fire station is 1.82. (b) The Y* coordinate of weighted center of gravity for new fire station is 2.06. (c) The factors might come into play when making the final decision is Zoning Considerations, Distance from other fire stations, Available space. Option D is correct.
To determine the location for the new fire station in Green Valley, we need to calculate the weighted center of gravity based on the coordinates and the number of homes in each neighborhood.
The X* coordinate of the weighted center of gravity can be calculated using the formula;
X* = (X₁ × N₁ + X₂ × N₂ + X₃ × N₃ + X₄ × N₄) / (N₁ + N₂ + N + N₄)
where X₁, X₂, X₃, X₄ are the X coordinates of the neighborhoods, and N₁, N₂, N₃, N₄ are the number of homes in each neighborhood.
Using the given data:
X* = (0.5 × 172 + 2 × 42 + 3 × 223 + 3 × 44) / (172 + 42 + 223 + 44)
X* ≈ 1.82
Therefore, the X* coordinate of the weighted center of gravity for the new fire station is approximately 1.82.
The Y* coordinate of the weighted center of gravity can be calculated using the same formula, replacing the X coordinates with Y coordinates:
Y* = (Y₁ × N₁ + Y₂ × N₂ + Y₃ × N₃ + Y₄ × N₄) / (N₁ + N₂ + N₃ + N₄)
Using the given data:
Y* = (3.5 × 172 + 0.5 × 42 + 1.5 × 223 + 1 × 44) / (172 + 42 + 223 + 44)
Y* ≈ 2.06
Therefore, the Y* coordinate of the weighted center of gravity for the new fire station is approximately 2.06.
When making the final decision on the location of the fire station, several other factors might come into play;
Zoning Considerations: The city needs to consider any zoning regulations or restrictions that might limit the potential locations for the fire station.
Distance from other fire stations: The proximity to existing fire stations is an important factor to ensure efficient coverage and response times across the area.
Available space: The availability of suitable land or buildings that meet the requirements for a fire station, such as accessibility, size, and infrastructure, should be considered.
Ultimately, the decision should take into account a combination of factors, including zoning considerations, distance from other fire stations, and available space. This comprehensive approach ensures that the fire station is strategically located to serve the four neighborhoods effectively and efficiently.
Hence, D. is the correct option.
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Why does water roll off a person's skin when the person gets out of a
swimming pool?
A. Because the skin is very smooth
B. Because water only sticks to other water molecules
C. Because water is full of hydrogen ions
D. Because the skin contains nonpolar lipid molecules
Answer:
your answer is D
Explanation:
Answer:
D. because the skin contains nonpolar lipid molecules
how does the structure of xylem relate to its function
Answer:
They lose their end walls so the xylem forms a continuous, hollow tube. They become strengthened by a substance called lignin . Lignin gives strength and support to the plant.
Write an essay about a
specific organism that is
endangered or threatened
and the reason for its
declining population.
Include any efforts made to
protect and conserve this
organism. At least 200 words
The answer is An endangered species is a type of organism that is threatened with extinction. Species are becoming endangered for two main reasons: habitat loss and loss of genetic variation.
Habitat loss can occur naturally. The dinosaurs, for example, lost their habitat about 65 million years ago. The hot, dry Cretaceous climate changed very quickly, most likely due to an asteroid impact on Earth. The asteroid's impact threw debris high into the atmosphere and reduced the amount of heat and light reaching Earth's surface. The dinosaurs could not adapt to this new, cooler habitat. The dinosaurs were threatened with extinction and then died out.
Human activities can also contribute to habitat loss. The development of settlements, industry and agriculture reduces the habitat of native organisms. This can be done in a number of ways.
Development may directly remove native habitats and species. In the Amazon rainforest in South America, developers have cleared hundreds of thousands of hectares. Clearing a piece of land means removing all trees and vegetation. The Amazon rainforest is being cleared for ranching, logging and urban use. That means the habitat can support fewer cougars. However, since large parts of the Sierra Nevada, Rocky and Cascade mountain ranges remain undeveloped, cougars are not in danger.
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The polymerase chain reactions (PCR) uses a heat resistant ____________ enzyme and free ____________ to create billions of copies of DNA. Because of its ____________ and specificity, it has numerous applications, including copying genes for the formation of ____________ needed to create transgenic organisms. PCR can also be used to amplify short ____________ DNA sequences from ancient organisms such as mummies or wooly mammoths. DNA fingerprinting is based on the idea that there are ____________ regions of DNA that have tandem repeats of different numbers, depending on the specific individual. These regions are amplified through PCR and visualized on a gel through ____________ . The ____________ the resulting pieces of DNA, the further they travel on the gel, resulting in a ____________ specific to that individual. These can be compared to determine identities of unknown victims, establish ____________ , identify the presence of viral infections, and determine predisposition for certain diseases
The polymerase chain reaction (PCR) uses a heat-resistant DNA polymerase enzyme and free nucleotides to create billions of copies of DNA. Because of its high accuracy and specificity, it has numerous applications, including copying genes for the formation of proteins needed to create transgenic organisms. PCR can also be used to amplify short, degraded DNA sequences from ancient organisms such as mummies or wooly mammoths.
DNA fingerprinting is based on the idea that there are specific regions of DNA that have tandem repeats of different numbers, depending on the specific individual. These regions are amplified through PCR and visualized on a gel through electrophoresis. The smaller the resulting pieces of DNA, the further they travel on the gel, resulting in a unique banding pattern specific to that individual. These can be compared to determine the identities of unknown victims, establish paternity/maternity, identify the presence of viral infections, and determine predisposition for certain diseases.
In summary, PCR is an essential tool for many molecular biology applications, including DNA fingerprinting. Its ability to selectively amplify specific DNA sequences has revolutionized the fields of forensic science, genetic research, and medical diagnostics. While it requires a long answer to fully describe, PCR's impact on modern science cannot be overstated.
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This system gets rid of waste material
Answer: The excretory system gets rid of waste and excess water.
There are major organs tasked with removing toxic substances from your body organs are kidneys, and lungs
Explanation:
Kidneys: ( One pair of organs in the abdomen). The kidneys act as a filter for the strain of urea and excess salts from the blood as it flows through the body to release them in the urine. The urine flows from the kidneys to the bladder through two thin tubes of muscles known as ureters. The bladder's main function is to store urine. Lungs: (one of the pair of organs in the chest that supplies the body with oxygen, and removes carbon dioxide from the body. Lungs bring fresh air (oxygen) into your body. and release carbon dioxide as well as unwanted materials. In respiration, food is broken down into carbon dioxide and water in the presence of oxygen by released oxygen.